Randomized controlled trial of pulse intravenous cyclophosphamide versus mycophenolate mofetil in the induction therapy of proliferative lupus nephritis.

Author: AhmadGhazali, GhazalliRozina, GohBak Leong, HooiLai Seong, LimTeck Onn, MoradZaki, OngLoke Meng, ShaariahWan, TanChwee Choon, TanSi Yen, TeoSue Mei, WongHin Seng

Paper Details 
Original Abstract of the Article :
BACKGROUND: The aim of the present study was to evaluate the efficacy of mycophenolate mofetil in the induction therapy of proliferative lupus nephritis. METHODS: Forty-four patients from eight centres with newly diagnosed lupus nephritis World Health Organization class III or IV were randomly assi...See full text at original site
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引用元:
https://doi.org/10.1111/j.1440-1797.2005.00444.x

データ提供:米国国立医学図書館(NLM)

Lupus Nephritis: A Comparative Study of Treatment Options

Lupus nephritis, a serious complication of systemic lupus erythematosus, can lead to kidney damage and even kidney failure. The quest for effective treatment options continues, with researchers exploring different medications to manage this complex condition. This study aimed to compare the efficacy of two medications, mycophenolate mofetil (MMF) and intravenous cyclophosphamide (IVC), in the induction therapy of proliferative lupus nephritis. The researchers conducted a randomized controlled trial involving 44 patients with newly diagnosed lupus nephritis, analyzing the effectiveness of each medication in achieving remission and improving renal function. The results showed that both MMF and IVC were effective in achieving remission, with similar improvements in various clinical markers.

Navigating the Complexities of Lupus Nephritis: Finding Effective Treatment Options

The study's findings, like a compass guiding us through the intricate pathways of lupus nephritis, offer valuable insights into the effectiveness of different treatment options. The researchers discovered that both MMF and IVC are effective in achieving remission and improving renal function, suggesting that healthcare professionals have more than one viable option for managing this complex condition. This knowledge empowers healthcare professionals to make informed decisions about treatment strategies based on individual patient characteristics and preferences.

Lupus Nephritis: Understanding the Treatment Landscape

Lupus nephritis can significantly impact the quality of life for individuals with systemic lupus erythematosus. This study provides valuable information for healthcare professionals and patients navigating the complex treatment landscape. The findings highlight the effectiveness of both MMF and IVC in achieving remission and improving renal function, offering hope for a brighter future for individuals with lupus nephritis.

Dr. Camel's Conclusion

This study, like a wellspring of knowledge in the desert of lupus nephritis, offers valuable insights into the effectiveness of different treatment options. The researchers discovered that both MMF and IVC are effective in achieving remission and improving renal function, offering a beacon of hope for those battling this complex condition. The findings serve as a valuable roadmap for healthcare professionals, enabling them to make informed decisions and guide patients towards a healthier future.

Date :
  1. Date Completed 2005-12-15
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

16221103

DOI: Digital Object Identifier

10.1111/j.1440-1797.2005.00444.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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