Paper Details
- Home
- Paper Details
A comparison of mazindol (Teronac) with diethylpropion in the treatment of exogenous obesity.
Author: CrowderD, DonaldJ F, MollaA L, MurphyJ E
Original Abstract of the Article :
Fifty obese patients were entered into a 12-week parallel group study of mazindol with diethylpropion in a general practice group. Both drugs produced weight loss, but patients on mazindol lost 19.9 lbs in 12 weeks, while those on diethylpropion lost 11.6 lbs, a statistically significant difference ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1177/030006057500300310
データ提供:米国国立医学図書館(NLM)
Mazindol vs. Diethylpropion: A Head-to-Head Comparison for Weight Loss
The battle of the bulge is a common struggle, and many seek effective weight loss solutions. This study compares the efficacy of two appetite suppressants, mazindol and diethylpropion, in treating exogenous obesity. The researchers conducted a 12-week parallel group study to determine which drug offered a more significant weight loss advantage.
Mazindol: A More Effective Appetite Suppressant
The results of the study showed that mazindol was significantly more effective than diethylpropion in promoting weight loss. Patients taking mazindol lost an average of 19.9 lbs in 12 weeks, compared to an average weight loss of 11.6 lbs in those taking diethylpropion. This difference was statistically significant, suggesting that mazindol may be a more effective option for weight management.
Weighing the Benefits and Side Effects
The study also investigated the side effects of each drug. Mazindol was associated with fewer side effects, primarily of an adrenergic, peripheral type. Diethylpropion, on the other hand, was associated with more central stimulant-type side effects. It's like choosing between a gentle camel ride through the desert and a wild, exhilarating dune buggy adventure. Each option has its own benefits and drawbacks.
Dr.Camel's Conclusion
This study provides valuable insights into the efficacy and safety of mazindol and diethylpropion for weight loss. Mazindol emerged as the more effective appetite suppressant, leading to greater weight loss and fewer side effects. However, it's important to note that the study involved a relatively small sample size, and further research with larger groups is needed to confirm these findings.
Date :
- Date Completed 1992-06-12
- Date Revised 2017-02-14
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.