A comparison of mazindol (Teronac) with diethylpropion in the treatment of exogenous obesity.

Author: CrowderD, DonaldJ F, MollaA L, MurphyJ E

Paper Details 
Original Abstract of the Article :
Fifty obese patients were entered into a 12-week parallel group study of mazindol with diethylpropion in a general practice group. Both drugs produced weight loss, but patients on mazindol lost 19.9 lbs in 12 weeks, while those on diethylpropion lost 11.6 lbs, a statistically significant difference ...See full text at original site
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引用元:
https://doi.org/10.1177/030006057500300310

データ提供:米国国立医学図書館(NLM)

Mazindol vs. Diethylpropion: A Head-to-Head Comparison for Weight Loss

The battle of the bulge is a common struggle, and many seek effective weight loss solutions. This study compares the efficacy of two appetite suppressants, mazindol and diethylpropion, in treating exogenous obesity. The researchers conducted a 12-week parallel group study to determine which drug offered a more significant weight loss advantage.

Mazindol: A More Effective Appetite Suppressant

The results of the study showed that mazindol was significantly more effective than diethylpropion in promoting weight loss. Patients taking mazindol lost an average of 19.9 lbs in 12 weeks, compared to an average weight loss of 11.6 lbs in those taking diethylpropion. This difference was statistically significant, suggesting that mazindol may be a more effective option for weight management.

Weighing the Benefits and Side Effects

The study also investigated the side effects of each drug. Mazindol was associated with fewer side effects, primarily of an adrenergic, peripheral type. Diethylpropion, on the other hand, was associated with more central stimulant-type side effects. It's like choosing between a gentle camel ride through the desert and a wild, exhilarating dune buggy adventure. Each option has its own benefits and drawbacks.

Dr.Camel's Conclusion

This study provides valuable insights into the efficacy and safety of mazindol and diethylpropion for weight loss. Mazindol emerged as the more effective appetite suppressant, leading to greater weight loss and fewer side effects. However, it's important to note that the study involved a relatively small sample size, and further research with larger groups is needed to confirm these findings.

Date :
  1. Date Completed 1992-06-12
  2. Date Revised 2017-02-14
Further Info :

Pubmed ID

162676

DOI: Digital Object Identifier

10.1177/030006057500300310

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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