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Nimesulide-induced fixed drug eruption.

Author: CadinhaS, Castel-BrancoM G, MalheiroD, RodriguesJ, VazM

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Nimesulide is a widely used and generally well-tolerated NSAID. The most common side effects are gastrointestinal, and pruritus and skin rash are the most frequent cutaneous reactions. There have been only a few reported cases of fixed drug eruptions due to nimesulide.
Paper Details　
Original Abstract of the Article :
Nimesulide is a cyclooxygenase (COX) inhibitor with a high degree of selectivity to COX-2. It is a widely used and well tolerated nonsteroidal antiinflammatory drug that also has analgesic and antipyretic properties. The most frequently reported side effects concern the gastrointestinal tract. Pruri...See full text at original site
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引用元：
https://doi.org/10.1157/13080933

データ提供：米国国立医学図書館（NLM）

Nimesulide: A Common Pain Reliever with a Rare Side Effect

This research examines the potential side effects of nimesulide, a widely used nonsteroidal anti-inflammatory drug (NSAID) that has analgesic and antipyretic properties. The study explores a rare but serious side effect of nimesulide, known as fixed drug eruption. While the most common side effects of nimesulide are gastrointestinal, fixed drug eruption is a severe skin reaction that can cause persistent and localized skin lesions.

The Case of Fixed Drug Eruption: A Lesson in Drug Safety

The authors present a case study of fixed drug eruption caused by nimesulide, highlighting the importance of being aware of the potential side effects of even commonly used medications. They emphasize the need for careful monitoring and prompt intervention in the event of a suspected adverse drug reaction.

A Reminder of Drug Safety: Being Vigilant About Side Effects

This study serves as a reminder to both healthcare professionals and patients about the potential for even well-tolerated drugs to cause unexpected side effects. It emphasizes the importance of individual responses to medication and the need for careful monitoring and early intervention.

Dr.Camel's Conclusion

This research is like a camel trekking across the desert, encountering a hidden danger that wasn't on the map. While nimesulide is generally safe, fixed drug eruption is a reminder that even familiar pathways can have unexpected hazards. This study encourages us to be vigilant and mindful of the potential for surprises, even when traveling well-traveled roads.
Date :
  1. Date Completed 2006-02-22
  2. Date Revised 2019-11-09
Further Info :

Pubmed ID

16287549

DOI: Digital Object Identifier

10.1157/13080933

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English

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