Combining physostigmine with meperidine for sedation and analgesia during colonoscopy.

Author: BeilinB, BinderY, ChervinskyA, MelzerE, SmolyarenkoV, YardeniI Z, ZeidelA

Paper Details 
Original Abstract of the Article :
Opiate or benzodiazepine drugs are often used during colonoscopy, but they are associated with respiratory depression and prolonged recovery. Physostigmine, a tertiary anticholinesterase agent, is known to enhance analgesia and to reverse the central nervous system depressant effects of these drugs....See full text at original site
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引用元:
https://doi.org/10.1055/s-2005-870217

データ提供:米国国立医学図書館(NLM)

Colonoscopy: A Symphony of Sedation and Analgesia

The field of gastroenterology is a fascinating realm, where we explore the intricate workings of our digestive system. Colonoscopy, a diagnostic procedure used to visualize the colon, often requires sedation and analgesia to ensure patient comfort. This study investigates the potential benefits of combining meperidine, an opioid analgesic, with physostigmine, an anticholinesterase agent, to enhance sedation and analgesia during colonoscopy.

A Harmonious Blend: Optimizing Sedation and Analgesia for Colonoscopy

The researchers compared the effects of meperidine alone with the combination of meperidine and physostigmine in patients undergoing colonoscopy. The findings suggest that combining these medications may offer advantages in terms of sedation and pain management. Physostigmine, known for its ability to enhance analgesia and reverse the central nervous system depressant effects of opioids, may contribute to a more comfortable and efficient colonoscopy experience. This research has the potential to improve patient care during colonoscopy, promoting a smoother and more comfortable experience for patients.

A Gentle Approach to Colonoscopy

The study highlights the importance of finding the right balance between sedation and analgesia to optimize patient comfort during colonoscopy. Just as a desert traveler seeks a balance between the scorching sun and the refreshing shade, healthcare professionals must carefully navigate the delicate interplay between sedation and pain management to ensure a positive patient experience.

Dr.Camel's Conclusion

This study explores the potential benefits of combining meperidine with physostigmine for sedation and analgesia during colonoscopy. The research suggests that this combination may enhance pain management and potentially improve the overall patient experience. The findings contribute to the ongoing efforts to optimize colonoscopy procedures, promoting patient comfort and ensuring a smooth and efficient diagnostic process.

Date :
  1. Date Completed 2006-03-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16329018

DOI: Digital Object Identifier

10.1055/s-2005-870217

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English

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