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Protective effects of betaxolol in eyes with kainic acid-induced neuronal death.

Author: CheonEun Woo, ChoChang Hyun, ChoGyeong Jae, ChoiWan Sung, ChungYoung Chul, KimYoon Sook, KwonJong Gil, ParkChang Hwan, YooJi Myong

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the neuroprotective effects of betaxolol on kainic acid (KA)-induced retinal damage in rats. Topical application of betaxolol was found to attenuate the retinal damage caused by KA.
Paper Details　
Original Abstract of the Article :
In the present study, we investigated whether betaxolol, a selective beta1-adrenoceptor antagonist, has neuroprotective effect on kainic acid (KA)-induced retinal damage. Neurotoxicities were induced in adult male rats by intravitreal injection of KA (total amount, 6 nmol). To examine the neuroprote...See full text at original site
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引用元：
https://doi.org/10.1016/j.brainres.2005.10.104

データ提供：米国国立医学図書館（NLM）

Protecting Retinal Cells: Exploring the Neuroprotective Potential of Betaxolol

Protecting the delicate tissues of the eye is crucial for maintaining vision. This research investigates the neuroprotective potential of betaxolol, a beta-blocker medication, in protecting retinal cells from damage caused by kainic acid (KA), a neurotoxin. The study explores the effects of betaxolol on retinal thickness and the number of specific types of cells in the retina.

Betaxolol's Neuroprotective Properties: A Potential for Retinal Health

The researchers found that betaxolol significantly attenuated the reduction in retinal thickness and the loss of specific types of cells in the retina caused by KA. These findings suggest that betaxolol may have neuroprotective effects in the retina, potentially offering a new avenue for protecting against retinal damage.

Preserving Vision: A Journey through the Eye's Landscape

This research offers a glimpse into the complex and intricate world of the eye. Imagine the retina as a vast desert, teeming with delicate structures and intricate pathways. Betaxolol, like a protective shield, may help to safeguard these structures from damage, ensuring the preservation of vision.

Dr. Camel's Conclusion

This research explores the intriguing potential of betaxolol as a neuroprotective agent in the retina. The findings highlight the importance of studying the effects of medications on various tissues, uncovering new applications and potentially improving the lives of those with vision-related challenges. As we continue to explore the vast desert of ophthalmic research, we must remain open to discovering new ways to preserve the precious gift of sight.

Date :
  1. Date Completed 2006-06-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16387283

DOI: Digital Object Identifier

10.1016/j.brainres.2005.10.104

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・Effects of betaxolol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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