Differential effect of glimepiride and rosiglitazone on metabolic control of type 2 diabetic patients treated with metformin: a randomized, double-blind, clinical trial.

Author: CiccarelliL, CiceroA F G, DerosaG, FerrariI, FogariE, GaddiA V, GhelfiM, PiccinniM N, SalvadeoS

Paper Details 
Original Abstract of the Article :
Accumulating evidence suggests that combination therapy using oral antidiabetic agents with different mechanisms of action may be highly effective in achieving and maintaining target blood glucose levels. The aim of our study is to evaluate the differential effect on glucose and lipid parameters of ...See full text at original site
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引用元:
https://doi.org/10.1111/j.1463-1326.2005.00480.x

データ提供:米国国立医学図書館(NLM)

Diabetes Management: Finding the Right Combination for Metabolic Control

Type 2 diabetes, a condition characterized by impaired glucose regulation, requires careful management to maintain optimal health. This study investigates the effectiveness of two different combinations of oral antidiabetic agents, glimepiride plus metformin and rosiglitazone plus metformin, in controlling blood glucose and lipid levels in patients with type 2 diabetes and metabolic syndrome.

The study's design, like a meticulous desert explorer carefully mapping out different routes, involved a randomized, double-blind, clinical trial. Researchers carefully compared the effectiveness of the two drug combinations, evaluating their impact on blood glucose, lipid profiles, and other metabolic parameters.

The findings, like a hidden oasis revealing a new path to better metabolic control, highlight the importance of personalized therapy in diabetes management.

Tailoring Treatment: Finding the Right Combination for Optimal Outcomes

This study underscores the importance of considering individualized treatment approaches for managing type 2 diabetes, emphasizing the potential benefits of combining different antidiabetic agents to optimize metabolic control.

This approach, like a skilled camel caravan adapting to the diverse landscapes of the desert, emphasizes the need for a personalized approach to diabetes management, taking into account individual patient characteristics and needs.

A Balanced Desert: Managing Blood Glucose and Lipid Levels

This research highlights the importance of managing both blood glucose and lipid levels in patients with type 2 diabetes.

It encourages us to consider the potential benefits of combination therapy in achieving optimal metabolic control, emphasizing the importance of a holistic approach to managing this complex condition.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness of different drug combinations for managing type 2 diabetes, highlighting the importance of personalized therapy and a holistic approach to metabolic control.

Date :
  1. Date Completed 2006-08-21
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

16448524

DOI: Digital Object Identifier

10.1111/j.1463-1326.2005.00480.x

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SNS
PICO Info
in preparation
Languages

English

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