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Comparative effects of terfenadine and loratadine in the treatment of hay fever.

Author: BuscagliaS, CanonicaG W, CiprandiG, IudiceA, RuffoniS, ToscaM A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

A study of 40 patients with seasonal allergies compared the effectiveness of terfenadine (120mg) and loratadine (10mg) over a 7-day period. Both drugs significantly improved symptoms, including nasal congestion, rhinorrhea, sneezing, and eye irritation (p<0.01). Terfenadine reduced symptoms by 69% compared to baseline, while loratadine reduced symptoms by 55%. While headache, fatigue, and sedation were reported in some loratadine patients, no side effects were observed with terfenadine. The study concluded that terfenadine is a safe and effective treatment for hay fever.
Paper Details　
Original Abstract of the Article :
This double-blind, double-dummy, parallel-group study was undertaken in 40 patients with seasonal allergic rhinoconjunctivitis during the 1990 hay fever season. The patients were randomized and treated for seven days with either 120 mg terfenadine or 10 mg loratadine, each drug taken once daily in t...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1669595

データ提供：米国国立医学図書館（NLM）

Terfenadine and Loratadine for Hay Fever

This research study ventures into the world of allergies, specifically exploring the effectiveness of terfenadine and loratadine in treating seasonal allergic rhinoconjunctivitis, more commonly known as hay fever. The study, like a skilled allergist navigating the pollen-filled desert of hay fever, compares the efficacy of these two antihistamines in managing the symptoms of this common allergy. The research seeks to provide a safe and effective treatment option for hay fever, a condition that can feel like a constant sandstorm in the nose and eyes.

Finding Relief from the Sandstorm of Hay Fever

The study found that both terfenadine and loratadine were effective in improving the severity of hay fever symptoms, with no significant difference between the two drugs. This finding offers valuable insights for allergists seeking to provide effective treatment options for their patients struggling with the discomfort of hay fever.

Navigating the Desert of Allergies

The study highlights the importance of finding effective and safe treatments for allergies. This research provides valuable information for managing the symptoms of hay fever and ensuring that patients can navigate the pollen-filled desert of allergies with greater comfort and relief.

Dr. Camel's Conclusion

The study reminds us that even in the face of the uncomfortable realities of hay fever, there is hope for relief. Effective antihistamines like terfenadine and loratadine offer valuable tools for managing the symptoms of this common allergy, helping patients navigate the desert of pollen with greater ease.

Date :
  1. Date Completed 1994-02-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1669595

DOI: Digital Object Identifier

1669595

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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