Myobloc for the treatment of benign essential blepharospasm in patients refractory to botox.

Author: DuttonJonathan J, RichardMichael J, WhiteJeffrey J

Paper Details 
Original Abstract of the Article :
PURPOSE: A small percentage of cases with essential blepharospasm or hemifacial spasm will become resistant to botulinum toxin A (Botox). We present our experience treating these patients with botulinum toxin B (Myobloc). METHODS: We reviewed all charts of patients in one physician's practice who r...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/16714924

データ提供:米国国立医学図書館(NLM)

Botox Alternatives: A New Frontier for Treating Blepharospasm

Treating essential blepharospasm, a condition characterized by involuntary eyelid spasms, is a complex and multifaceted challenge. This study explores the use of botulinum toxin B, known as Myobloc, as an alternative treatment option for patients who have become resistant to the commonly used botulinum toxin A (Botox). The researchers aimed to evaluate the efficacy and safety of Myobloc in this specific patient population. This study examines a group of patients who experienced treatment resistance to Botox and were treated with Myobloc. Their experience with Myobloc was meticulously documented and assessed for effectiveness, duration of effect, and the occurrence of side effects.

Myobloc: A Promising Alternative, But With Trade-offs

The study found that Myobloc provided a significant benefit to patients who had become resistant to Botox, offering relief from spasms for an average duration of 7.3 weeks. However, Myobloc also exhibited a higher rate of side effects compared to Botox, including pain upon injection, ptosis (drooping eyelids), and facial or mouth droop. This suggests that Myobloc may spread more diffusely than Botox, leading to a greater range of potential side effects.

Navigating the Treatment Options for Blepharospasm

The results of this study demonstrate that Myobloc can be a valuable treatment option for patients with blepharospasm who have become resistant to Botox. However, the trade-off between efficacy and side effects must be carefully considered. For patients facing blepharospasm, careful consultation with a physician is essential to determine the most appropriate treatment plan. Remember, choosing the right treatment for your condition is a journey, not a sprint. It's important to consult with a healthcare professional to ensure that the path you choose is safe and effective.

Dr. Camel's Conclusion

Imagine Botox as a trusty camel that's always carried you through the desert of blepharospasm. But sometimes, even the best camel can tire, and you need a new steed. Myobloc, like a spirited young camel, offers a new path, but comes with its own quirks. Remember to weigh the pros and cons carefully before embarking on this new adventure. With a good plan and a knowledgeable guide, you can overcome the challenges of blepharospasm and find the best treatment path for you.

Date :
  1. Date Completed 2006-06-26
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

16714924

DOI: Digital Object Identifier

00002341-200605000-00005

Related Literature

SNS
PICO Info
in preparation
Languages

English

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