Severe hepatic side effects of ezetimibe.

Author: BecxMarco C J M, KuypersKarel C, SeldenrijkCees A, StolkMark F J

Paper Details 
Original Abstract of the Article :
BACKGROUND AND AIMS: Ezetimibe was introduced recently as a new class of cholesterol-lowering drugs. Until now only limited increases of transaminase levels were reported. METHODS: We studied 2 patients with severe hepatic side effects of ezetimibe in a general community hospital. RESULTS: Ezetimi...See full text at original site
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引用元:
https://doi.org/10.1016/j.cgh.2006.04.014

データ提供:米国国立医学図書館(NLM)

Ezetimibe: A Cautionary Tale of Potential Hepatic Side Effects

Ezetimibe, a cholesterol-lowering drug, has been hailed for its efficacy in managing hypercholesterolemia. However, this research highlights the potential for severe hepatic side effects associated with ezetimibe use. The authors present two case reports of patients who experienced significant liver dysfunction after taking ezetimibe, emphasizing the importance of careful monitoring and early intervention to minimize the risk of complications. This study serves as a reminder of the potential for unexpected side effects even with widely used medications.

Ezetimibe: Potential for Liver Toxicity

This research underscores the potential for ezetimibe to cause severe hepatic side effects, including cholestatic hepatitis and acute autoimmune hepatitis. The authors emphasize the need for careful monitoring of liver function in patients taking ezetimibe, particularly those with pre-existing liver conditions or a history of drug-induced liver injury. This study highlights the importance of vigilant monitoring and early intervention to minimize the risk of liver complications associated with ezetimibe use.

Navigating the Risks and Benefits of Cholesterol-Lowering Medications

This research reminds us that even seemingly safe medications can have potential side effects. While ezetimibe has been shown to effectively lower cholesterol levels, this study highlights the need for a balanced approach to managing cholesterol levels, weighing the potential benefits of medication against the risks of potential side effects. The authors emphasize the importance of open communication between patients and healthcare providers to make informed decisions about medication use and manage potential risks effectively.

Dr.Camel's Conclusion

Just like a desert traveler must be aware of the dangers of dehydration, healthcare providers and patients must be mindful of the potential side effects of medications, even those commonly used. This research serves as a reminder of the importance of careful monitoring and early intervention to ensure the safe and effective use of medications.

Date :
  1. Date Completed 2006-09-28
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16797241

DOI: Digital Object Identifier

10.1016/j.cgh.2006.04.014

Related Literature

SNS
PICO Info
in preparation
Languages

English

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