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Long-term followup of a randomized study of locally advanced prostate cancer treated with combined orchiectomy and external radiotherapy versus radiotherapy alone.

Author: DamberJan-Erik, GranforsTorvald, ModigHans, TomicRadisa

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared two treatment approaches for advanced prostate cancer: 1) surgery to remove the testicles (orchiectomy) combined with radiation therapy and 2) radiation therapy alone, followed by hormone therapy (castration) when the cancer progressed. The study aimed to determine the effectiveness of immediate versus delayed hormone treatment in this type of prostate cancer.
Paper Details　
Original Abstract of the Article :
In a randomized study we compared the combination of orchiectomy and radiotherapy to radiotherapy alone as treatment for locally advanced prostate cancer. Patients who were treated only with radiotherapy initially underwent castration therapy at clinical progression, providing the opportunity to com...See full text at original site
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引用元：
https://doi.org/10.1016/j.juro.2006.03.092

データ提供：米国国立医学図書館（NLM）

Locally Advanced Prostate Cancer: A Long Journey Through the Desert

Prostate cancer, like a vast and unforgiving desert, can present a formidable challenge for patients. This research, like a long and arduous journey, explores the long-term outcomes of two treatment approaches for locally advanced prostate cancer: combined orchiectomy and external radiotherapy versus radiotherapy alone. The researchers analyzed data from a randomized study, seeking to determine the effectiveness of each approach over time.

Immediate vs. Deferred Endocrine Intervention: Two Paths in the Desert

The study found that both treatment approaches were effective in managing locally advanced prostate cancer, but the timing of endocrine intervention had a significant impact on long-term outcomes. Patients who received immediate endocrine intervention with orchiectomy had a better survival rate compared to those who received deferred endocrine intervention. This finding is like discovering two paths through the desert, one offering a more direct and successful route to the oasis of survival.

Navigating the Desert of Prostate Cancer Treatment: A Guide for Patients

This research provides valuable insights into the long-term management of locally advanced prostate cancer. The study highlights the importance of carefully considering the timing of endocrine intervention in the treatment plan, as it can significantly impact survival outcomes. This research is like a compass in the desert, guiding us towards more effective treatment strategies for prostate cancer.

Dr. Camel's Conclusion

This research takes us on a long journey through the desert of prostate cancer treatment, exploring the long-term outcomes of two different approaches. The findings highlight the importance of early and comprehensive treatment strategies in maximizing survival rates for patients with locally advanced prostate cancer. This study is like a desert caravan, carrying the hope of improved outcomes and a longer journey through the desert of this challenging disease.

Date :
  1. Date Completed 2006-08-29
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

16813885

DOI: Digital Object Identifier

10.1016/j.juro.2006.03.092

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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