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The metabolism of mesalamine and its possible use in colonic diverticulitis as an anti-inflammatory agent.
Author: CohenHillel D, DasKiron M
Original Abstract of the Article :
5-Aminosalicylic acid (5-ASA) is the mainstay of therapy for inflammatory bowel disease (IBD), particularly ulcerative colitis. 5-ASA is the active moiety in sulfasalazine, which was initially developed for the treatment of rheumatoid arthritis more than 60 years ago, by linking 5-ASA with sulfapyri...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/16885699
データ提供:米国国立医学図書館(NLM)
Mesalamine: A Desert Oasis for Inflammatory Bowel Disease
Inflammatory bowel disease (IBD), a group of conditions that cause inflammation in the digestive tract, can be a debilitating experience. Imagine a desert oasis where the water has turned bitter and the air is thick with dust – that's what IBD feels like. This article, like a camel seeking a cure for a desert ailment, explores the potential of mesalamine, a medication commonly used for IBD, for treating colonic diverticulitis, a condition where pouches in the colon become inflamed.
Mesalamine: A Potential Remedy for Colonic Diverticulitis
The authors, like desert healers with a deep understanding of medicinal plants, discuss the development and use of mesalamine, a derivative of 5-aminosalicylic acid (5-ASA). They highlight the drug's anti-inflammatory properties and its potential for treating uncomplicated acute diverticulitis. It's like discovering a new herb in the desert with healing powers.
Exploring New Applications: A Journey of Discovery
This article demonstrates the importance of ongoing research to explore new applications for existing medications. It's like a desert explorer venturing into uncharted territory, seeking new discoveries. The authors encourage further investigation into the use of mesalamine for treating colonic diverticulitis, potentially offering a new oasis of relief for those suffering from this condition.
Dr. Camel's Conclusion
This study is a reminder that the search for effective treatments is a continuous journey. It encourages us to remain open to new possibilities and explore the potential benefits of existing medications for treating different conditions. It's like a camel adapting to a changing desert landscape, always seeking new sources of sustenance and survival.
Date :
- Date Completed 2006-11-28
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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