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Comparison of three rating scales as outcome measures for treatment trials of depression in Alzheimer disease: findings from DIADS.

Author: BakerAlva S, BayR Curt, LyketsosConstantine G, MayerLawrence S, PolitisAntonios, RabinsPeter V, SteeleCynthia, SteinbergMartin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

The study discussed the challenges of measuring treatment outcomes in studies of depression in Alzheimer's disease (AD), highlighting the importance of using scales that can detect a difference between treatment and control effects.
Paper Details　
Original Abstract of the Article :
Major depression affects about 25% of patients with Alzheimer's disease (AD) and has serious adverse consequences for patients as well as caregivers. Studies of treatments for depression in AD, like most treatment studies, depend on the ability of the scales used to measure outcome to detect a diffe...See full text at original site
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引用元：
https://doi.org/10.1002/gps.1583

データ提供：米国国立医学図書館（NLM）

Rating Scales for Depression in Alzheimer's Disease: A Comparative Study

This research delves into the [assessment of depression in Alzheimer's disease (AD)], examining the efficacy of different [rating scales] in measuring treatment outcomes. The study employed a [comparative analysis] to evaluate the performance of three [rating scales] in [detecting treatment effects in clinical trials]. The findings suggest that [all three scales are effective in measuring treatment outcomes], providing valuable tools for evaluating the effectiveness of interventions for depression in AD.

The Importance of Accurate Assessment in Alzheimer's Disease

The study emphasizes the [crucial role of accurate assessment] in understanding and managing [depression in AD]. The findings highlight the importance of [selecting appropriate rating scales] for clinical trials, as these tools play a significant role in [identifying effective treatments] and [improving the quality of life for patients].

Navigating the Maze of Alzheimer's Disease: Supporting Individuals and Caregivers

This study sheds light on the complexities of [managing depression in AD] and the importance of [choosing the right tools for assessment]. It underscores the need for [compassionate and supportive care] for individuals with AD and their caregivers, as they face the challenges of this disease.

Dr. Camel's Conclusion

Just as a camel navigating a vast desert relies on landmarks and guides, healthcare providers need reliable tools to navigate the complexities of Alzheimer's disease. This study explores those tools, highlighting the significance of accurate assessment and appropriate treatment approaches in improving the lives of individuals with this condition.
Date :
  1. Date Completed 2007-08-20
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

16955427

DOI: Digital Object Identifier

10.1002/gps.1583

Related Literature

Article Analysis
・Effective treatment of alzheimer's disease
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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