Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model.

Author: BedenicBranka, BubonjaMarina, BudimirAna, TopicMarijana

Paper Details 
Original Abstract of the Article :
BACKGROUND: In this investigation, the urine samples obtained in a single oral-dose pharmacokinetic study were examined for their bactericidal activity against a range of relevant urinary tract pathogens. METHODS: Six healthy volunteers received a single oral dose of ten oral antibiotics available ...See full text at original site
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引用元:
https://doi.org/10.1159/000095969

データ提供:米国国立医学図書館(NLM)

Urinary Bactericidal Activity of Oral Antibiotics against Urinary Tract Pathogens

This research explores the important area of [urinary tract infections (UTIs)] and the efficacy of oral antibiotics in treating these common infections. The researchers, like diligent detectives investigating a bacterial crime scene, examined the [bactericidal activity] of various oral antibiotics against [common urinary tract pathogens] in an [ex vivo model]. Their findings offer valuable insights into the effectiveness of these antibiotics in treating UTIs.

Evaluating the Bactericidal Activity of Oral Antibiotics in Treating UTIs

The study, like a carefully controlled experiment in a desert laboratory, found that [all antibiotics] displayed significant [bactericidal activity] against [non-extended spectrum beta-lactamase Escherichia coli and Proteus mirabilis]. The researchers also found that [fluoroquinolones] exhibited [high and persisting levels of bactericidal activity] against [all gram-negative bacteria and Staphylococcus saprophyticus]. This research provides valuable information for healthcare providers in selecting the most effective antibiotics for treating UTIs.

The Importance of Understanding Antibiotic Resistance in UTI Treatment

This study highlights the importance of understanding [antibiotic resistance] in treating [UTIs]. The researchers emphasize the need for careful selection of antibiotics based on the specific pathogen involved and its susceptibility profile. Just as a camel must adapt its route based on the terrain, healthcare providers must adapt their treatment approach based on the specific characteristics of each UTI.

Dr. Camel's Conclusion

This research offers valuable insights into the [bactericidal activity] of different oral antibiotics against [common urinary tract pathogens]. The findings underscore the importance of choosing the right antibiotic based on [susceptibility testing] and the need for vigilance in combating [antibiotic resistance]. Just as a camel relies on its adaptability to survive in the harsh desert environment, healthcare professionals must remain adaptable and informed in their efforts to manage UTIs effectively.

Date :
  1. Date Completed 2007-02-13
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17008781

DOI: Digital Object Identifier

10.1159/000095969

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Languages

English

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