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Short-term effects of tetrabenazine on chorea associated with Huntington's disease.

Author: DavidsonAnthony, HunterChristine, JankovicJoseph, KenneyChristopher

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This observational study assessed the short-term effects of tetrabenazine (TBZ) on choreic movements in Huntington's disease patients. TBZ reduced chorea scores by an average of 42.4% for approximately 5 hours following a single dose.
Paper Details　
Original Abstract of the Article :
We sought to assess the short-term clinical effects of tetrabenazine (TBZ) on choreic movements in Huntington's disease patients. A total of 10 patients on stable doses of TBZ were enrolled in this observational study. Patients took their evening dose of TBZ and presented the next day to the Baylor ...See full text at original site
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引用元：
https://doi.org/10.1002/mds.21161

データ提供：米国国立医学図書館（NLM）

Examining the Short-Term Effects of Tetrabenazine on Huntington's Disease

This study delves into the intriguing realm of [neurology] and [movement disorders], focusing on the effects of tetrabenazine (TBZ) on chorea, a common symptom of Huntington's disease. The researchers employed an [observational study] design to evaluate the short-term impact of TBZ on patients with Huntington's disease. The study revealed that [TBZ treatment effectively reduced chorea symptoms in patients with Huntington's disease], providing temporary relief from the debilitating movements. This finding underscores the potential of TBZ as a therapeutic option for managing chorea in this challenging condition.

Potential Benefits of Tetrabenazine for Huntington's Disease

The study's results indicate that [TBZ can significantly improve chorea symptoms for several hours, providing meaningful relief to patients]. This suggests that TBZ may play a valuable role in managing the symptoms of Huntington's disease and improving the quality of life for affected individuals.

Navigating the Desert of Huntington's Disease

Just as a camel navigates the treacherous sands of the desert, researchers are constantly seeking new paths to combat the challenges of Huntington's disease.

Dr.Camel's Conclusion

This study illuminates the potential of TBZ in managing chorea, a relentless symptom of Huntington's disease. By understanding the intricacies of these neurological pathways, we can pave the way for more effective treatments, offering hope to those struggling with this debilitating condition.

Date :
  1. Date Completed 2007-04-05
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

17078062

DOI: Digital Object Identifier

10.1002/mds.21161

Related Literature

Article Analysis
・Effects of tetrabenazine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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