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Continuous infusion versus bolus administration of steroids in severe attacks of ulcerative colitis: a randomized, double-blind trial.
Author: AccadiaLaura, AndriulliAngelo, AnneseVito, BossaFabrizio, CarusoNazario, FiorellaSerafina, NapolitanoGrazia, ValvanoMaria Rosa
Original Abstract of the Article :
BACKGROUND: In patients with severe attacks of ulcerative colitis (UC), IV steroids represent the first-line treatment, leading to clinical improvement in approximately 50-60% of patients. AIM: The aim of this study was to prospectively compare the efficacy and safety of different modalities of ste...See full text at original site
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引用元:
https://doi.org/10.1111/j.1572-0241.2006.01007.x
データ提供:米国国立医学図書館(NLM)
Steroid Administration for Ulcerative Colitis: Bolus vs. Infusion
This study explores the effectiveness of different steroid administration methods in treating severe ulcerative colitis (UC). It's like exploring different ways to navigate a treacherous desert, each with its own risks and rewards. The study aims to determine the most effective method for delivering steroids to patients with UC.
Comparing Steroid Administration Methods
The study compared the efficacy and safety of bolus injection and continuous infusion of methylprednisolone in patients with severe UC. It's like comparing two different caravans, each equipped with different tools for a desert journey. The study found that both methods were equally effective in inducing clinical remission, suggesting that the choice of administration method can be tailored to individual patients.
Finding the Right Approach for Ulcerative Colitis
This research provides valuable information for healthcare providers treating patients with severe UC. It's like having a map with two possible routes, allowing them to choose the most effective strategy for each patient. The study emphasizes the importance of individualized treatment approaches and the need for further research to understand the long-term implications of different steroid administration methods.
Dr. Camel's Conclusion
This study examined different methods for administering steroids to patients with severe ulcerative colitis. It's like navigating a desert, exploring different routes to reach a safe oasis. The study suggests that both bolus and infusion methods are effective and that the choice can be tailored to individual patient needs. Further research is needed to better understand the long-term effects of each approach.
Date :
- Date Completed 2007-04-26
- Date Revised 2007-03-05
Further Info :
English
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