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A prospective, randomised double-blind crossover study to examine the efficacy of strontium-89 in pain palliation in patients with advanced prostate cancer metastatic to bone.

Author: AckeryD M, BaylyR J, KeelingD H, LewingtonV J, MacleodP M, McEwanA J, PorterA T, ZivanovicM A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated strontium-89 chloride for treating bone pain in prostate cancer patients. A double-blind study showed strontium-89 was significantly better than a placebo in relieving pain. This suggests a potential benefit for using strontium-89 in managing pain from bone metastases.
Paper Details　
Original Abstract of the Article :
The palliative efficacy of strontium-89 chloride has been evaluated in a prospective double-blind crossover study comparing it with stable strontium as placebo in 32 patients with prostate cancer metastatic to bone. Response was assessed 5 weeks after each treatment. 26 patients were evaluable. Comp...See full text at original site
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引用元：
https://doi.org/10.1016/0277-5379(91)90257-e

データ提供：米国国立医学図書館（NLM）

Strontium-89: A Promising Solution for Pain Relief in Bone Metastases

The realm of [cancer pain management] is continually searching for new and effective ways to alleviate suffering. This study investigates the efficacy of [strontium-89] in the treatment of [bone metastases] associated with [advanced prostate cancer]. It's like discovering a hidden spring in the desert, offering a source of relief from the scorching pain.

The researchers conducted a [prospective double-blind crossover study] comparing [strontium-89] to [placebo] in [32 patients]. They found that [strontium-89] was significantly more effective in providing [pain relief] than [placebo], a significant finding for patients struggling with this debilitating condition. It's like finding a cool breeze in the middle of a sandstorm, providing a moment of respite from the unrelenting pain.

A Hopeful Solution for Bone Metastases

The study highlights the potential of [strontium-89] as a valuable tool for managing [bone metastases] associated with [prostate cancer]. It's like finding a new oasis in the desert, offering a source of hope and relief for patients struggling with this challenging diagnosis.

A New Weapon in the Fight Against Cancer Pain

The development of [strontium-89] represents a significant advance in the fight against [cancer pain]. It offers a new and potentially effective treatment option for patients struggling with [bone metastases], bringing them a much-needed respite from their suffering. It's like finding a hidden weapon in the desert, a powerful tool for combating the relentless pain associated with cancer.

Dr. Camel's Conclusion

This study provides a beacon of hope for patients struggling with [bone metastases] associated with [prostate cancer]. The efficacy of [strontium-89] in providing [pain relief] is a testament to the power of medical innovation in the face of suffering. It's like finding a hidden spring in the desert, offering a much-needed source of relief and a promise of a better future for patients facing this challenging diagnosis.

Date :
  1. Date Completed 1991-10-30
  2. Date Revised 2019-07-18
Further Info :

Pubmed ID

1716935

DOI: Digital Object Identifier

10.1016/0277-5379(91)90257-e

Related Literature

Article Analysis
・Effects of strontium-89 chloride
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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