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[Preinduction in the treatment of patients with malignant lymphoma].

Author: AvilésA, Diáz-MaqueoJ C, GarcíaE L, GuzmánR, TalaveraA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study of 98 patients with malignant lymphoma compared the effectiveness of a preinduction regimen of low-dose methotrexate followed by standard chemotherapy (CHOP-Bleo) to standard chemotherapy alone. The preinduction group had fewer early deaths, a higher complete remission rate, longer remission duration, and better overall survival compared to the conventional chemotherapy group. While the preinduction regimen had acceptable side effects, the severity of side effects was similar in both groups receiving standard chemotherapy. The study suggests that a preinduction regimen of low-dose methotrexate is a beneficial approach for patients with malignant lymphoma.
Paper Details　
Original Abstract of the Article :
Prospective clinical study of ninety-eight patients with untreated malignant lymphoma were randomly assigned to be treated wether with combined chemotherapy: cyclophosphamide, hidroxidaunil adriamycin, vincristine, prednisone and bleomycin (CHOP-Bleo) or with two low-dose of methotrexate as preinduc...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1720407

データ提供：米国国立医学図書館（NLM）

Preinduction in Malignant Lymphoma: A Trailblazer in the Desert of Treatment

The desert of [malignant lymphoma] treatment is a challenging landscape, often requiring a combination of therapies to effectively combat this disease. This study investigates the potential of [preinduction chemotherapy] as a novel approach to improve treatment outcomes. The researchers conducted a [prospective clinical study] comparing two groups of patients with untreated malignant lymphoma: one receiving conventional chemotherapy and the other receiving a preinduction regimen followed by the same chemotherapy. The results revealed that preinduction therapy was associated with fewer early deaths, higher rates of complete remission, longer remission duration, and improved survival. This research suggests that preinduction therapy could be a valuable tool in the arsenal of clinicians treating malignant lymphoma, offering a potential path towards improved outcomes for patients.

Preinduction in Malignant Lymphoma: A Trailblazer in the Desert of Treatment

This study provides evidence for the potential benefits of preinduction chemotherapy in treating malignant lymphoma. The researchers found that preinduction therapy was associated with improved outcomes, including fewer early deaths, higher rates of complete remission, longer remission duration, and improved survival. These findings suggest that preinduction therapy may be a valuable addition to the treatment strategies for malignant lymphoma.

Preinduction in Malignant Lymphoma: A Trailblazer in the Desert of Treatment

This research highlights the importance of exploring novel approaches to improve treatment outcomes in malignant lymphoma. The study's findings suggest that preinduction therapy may be a valuable tool for clinicians, offering a potential path towards better outcomes for patients. This research underscores the need for continued investigation into innovative treatment strategies to combat this challenging disease.

Dr. Camel's Conclusion

This research offers a promising glimpse into the potential benefits of preinduction therapy in treating malignant lymphoma. By exploring new pathways and adapting treatment strategies, clinicians can continue to navigate the desert of cancer treatment, seeking to improve outcomes for patients and offer hope for a brighter future.

Date :
  1. Date Completed 1992-01-03
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

1720407

DOI: Digital Object Identifier

1720407

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Article Analysis
・Effective treatment of lymphoma
SNS
PICO Info
in preparation
Languages

Spanish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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