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Low-dose methazolamide and intraocular pressure.

Author: BeckerB, KassM A, ShinD H, StoneR A, ZimmermanT J

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Methazolamide, a carbonic anhydrase inhibitor, was effective in reducing intraocular pressure in patients with increased intraocular pressure. Acetazolamide, another carbonic anhydrase inhibitor, was more effective but also caused more systemic acidosis and side effects.
Paper Details　
Original Abstract of the Article :
Sixteen patients with increased intraocular pressure (over 20 mm Hg) received 25 and 50 mg of oral methazolamide, twice daily, during consecutive weeks and then 500 mg (Sequels) of acetazolamide. The two methazolamide regimens produced significant decreases in intraocular pressure. Acetazolamide tre...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9394(77)90134-9

データ提供：米国国立医学図書館（NLM）

Methazolamide: A Tiny Pill for Eye Pressure

This study, published in 1978, investigates the effects of methazolamide, a medication used to reduce intraocular pressure, a condition that can damage the optic nerve and lead to vision loss. The researchers studied the effects of methazolamide in 16 patients with elevated intraocular pressure, comparing it to acetazolamide, another medication used for this purpose.

Methazolamide: A Gentle Approach

The study found that methazolamide, in lower dosages (25 and 50 mg), effectively reduced intraocular pressure, while acetazolamide, a more potent medication, produced a greater decrease in pressure but was associated with more side effects. These findings suggest that methazolamide, like a gentle desert breeze, can provide effective pressure control without causing significant side effects.

Navigating the Desert of Eye Pressure

It is important to remember that every camel's eyes react differently to the desert sun. The right treatment for you will depend on your individual needs and health history. Always consult with a healthcare professional to determine the most suitable treatment for your eye pressure.

Dr. Camel's Conclusion

This study, like a caravan navigating a desert landscape, provides valuable insights into the effectiveness of methazolamide in managing intraocular pressure. The research highlights the potential of methazolamide to offer a gentle and effective treatment option, offering a beacon of hope for those seeking relief from this challenging condition.
Date :
  1. Date Completed 1977-07-29
  2. Date Revised 2019-06-27
Further Info :

Pubmed ID

17301

DOI: Digital Object Identifier

10.1016/0002-9394(77)90134-9

Related Literature

Article Analysis
・Side Effects of methazolamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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