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Nicotine lozenges for the treatment of smokeless tobacco use.

Author: CroghanIvana T, DaleLowell C, EbbertJon O, HurtRichard D, RasmussenDonna F, SchroederDarrell R, SeversonHerbert, Vander WegMark W

Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Nicotine lozenges, while effective for cigarette smokers, have not been evaluated for smokeless tobacco (ST) users. An open-label trial suggests the 4-mg nicotine lozenge may be promising for treating withdrawal symptoms and craving in ST users, leading to a 53% abstinence rate at 12 weeks and 47% at 6 months.
Paper Details　
Original Abstract of the Article :
Nicotine lozenges have been shown to increase tobacco abstinence rates in cigarette smokers, but they have not been evaluated in smokeless tobacco (ST) users. We conducted an open-label, one-arm, phase II clinical trial to evaluate the efficacy of the 4-mg nicotine lozenge for the treatment of withd...See full text at original site
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引用元：
https://doi.org/10.1080/14622200601080349

データ提供：米国国立医学図書館（NLM）

Nicotine Lozenges: A New Approach to Smokeless Tobacco Cessation

The cessation of [smokeless tobacco use] often involves a complex interplay of factors, including physical dependence and behavioral habits. This research explores the potential of [nicotine lozenges] as a treatment for withdrawal symptoms and craving associated with smokeless tobacco abstinence. The study reports a significant decrease in craving among participants, along with a moderate rate of biochemically confirmed abstinence at the end of treatment. The authors suggest that nicotine lozenges may be a promising tool for assisting individuals in quitting smokeless tobacco use.

A Stepping Stone to Tobacco Freedom

This research provides encouraging results for individuals seeking to quit smokeless tobacco. Just as a camel uses a series of oases as stepping stones across a vast desert, nicotine lozenges can serve as a valuable tool in the process of quitting. The study's findings suggest that these lozenges can help manage withdrawal symptoms, making the journey to tobacco-free living a bit smoother.

Making the Transition to a Tobacco-Free Life

This research highlights the importance of providing appropriate support and tools to individuals seeking to quit smokeless tobacco. It suggests that nicotine lozenges, combined with behavioral interventions and counseling, may be a valuable strategy for promoting long-term cessation.

Dr. Camel's Conclusion

This research on nicotine lozenges is a promising step in the ongoing fight against smokeless tobacco use. Just as a camel adapts to the harsh desert environment, individuals seeking to quit tobacco need support and tools to navigate the transition. This research offers hope that nicotine lozenges can play a significant role in helping individuals achieve tobacco-free living.

Date :
  1. Date Completed 2007-04-05
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

17365754

DOI: Digital Object Identifier

10.1080/14622200601080349

Related Literature

Article Analysis
・Effective treatment of smokeless tobacco
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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