Paper Details

  1. Home
  2. Paper Details

The effect of intravenous administration of dexamethasone on postoperative pain, nausea, and vomiting after intrathecal injection of meperidine.

Author: Akbarian-TefaghiNiloufar, EsfehaniFatimah, MovafeghAli, NaviAli, SadeghiMustafa, SoroushAhmad Reza

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Administration of IV dexamethasone before intrathecal meperidine injection enhanced analgesia and reduced postoperative nausea and vomiting (PONV). In a randomized study, the dexamethasone group showed significantly lower total dose of diclofenac, visual analog scale pain score, and incidence of PONV.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Different drugs have been used to enhance postoperative neuraxial opioid analgesia and reduce adverse effects. METHODS: We randomized 60 patients into 2 groups to receive either 2 mL saline or 0.1 mg/kg dexamethasone IV before the administration of intrathecal anesthesia (15 mg and mepe...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1213/01.ane.0000257926.07491.55

データ提供：米国国立医学図書館（NLM）

Intrathecal Meperidine: Enhancing Analgesia and Reducing Side Effects

Postoperative pain is a common challenge, like a desert traveler struggling with the heat and discomfort of a long journey. This study explores the potential of dexamethasone to enhance the analgesic effects of intrathecal meperidine, a pain-relieving medication administered into the spinal fluid, while reducing side effects such as nausea and vomiting. The researchers conducted a randomized controlled trial to compare the effects of intravenous dexamethasone with a placebo group. They found that dexamethasone significantly reduced postoperative pain, nausea, and vomiting, suggesting that it may enhance the analgesic effects of intrathecal meperidine while mitigating its adverse effects.

Dexamethasone: A Potential Ally in Postoperative Pain Management

The study suggests that dexamethasone could be a valuable adjunct to intrathecal meperidine for postoperative pain management. By reducing pain and minimizing side effects, dexamethasone could improve patient comfort and recovery after surgery.

A Smoother Recovery: Minimizing Postoperative Discomfort

This research highlights the potential of dexamethasone to improve the postoperative experience for patients. By reducing pain, nausea, and vomiting, dexamethasone can contribute to a more comfortable and efficient recovery.

Dr. Camel's Conclusion

Like a cool breeze in the desert, dexamethasone may provide relief from the heat and discomfort of postoperative pain. This study suggests that dexamethasone can enhance the analgesic effects of intrathecal meperidine while minimizing side effects, leading to a more comfortable and efficient recovery for patients.

Date :
  1. Date Completed 2007-04-12
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

17377120

DOI: Digital Object Identifier

10.1213/01.ane.0000257926.07491.55

Related Literature

Article Analysis
・Effects of meperidine injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.