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Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: a double-blind, randomized, placebo-controlled trial.

Author: AllaartCornelia F, BreedveldFerdinand C, HuizingaTom W J, HulsmansHarry M J, LardLeroy R, PeetersAndré J, RondayH Karel, SpeyerIrene, ToesRené E M, VisserKaren, WestedtMarie-Louise, van AkenJill, van DongenHenrike

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Methotrexate treatment in patients with undifferentiated arthritis postponed the diagnosis of RA and retarded radiographic joint damage.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To determine whether patients with undifferentiated arthritis (UA; inflammatory, nontraumatic arthritis that cannot be diagnosed using current classification criteria) benefit from treatment with methotrexate (MTX). METHODS: The PRObable rheumatoid arthritis: Methotrexate versus Placebo ...See full text at original site
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引用元：
https://doi.org/10.1002/art.22525

データ提供：米国国立医学図書館（NLM）

Methotrexate: A Potential Oasis in the Desert of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is like a relentless desert storm, causing pain, inflammation, and joint damage. This study investigates the effectiveness of methotrexate (MTX), a commonly used medication for RA, in patients with probable RA, exploring the potential for MTX to slow down the progression of this debilitating disease.

The researchers conducted a double-blind, placebo-controlled trial, randomly assigning participants to receive either MTX or a placebo. They found that MTX effectively delayed the diagnosis of RA and slowed down the progression of joint damage, suggesting a potential benefit for patients with probable RA. It's like finding a hidden oasis in the desert, offering a chance for respite and a chance to regain control of their health.

This study suggests that MTX could be a valuable treatment option for patients with probable RA, potentially mitigating the long-term effects of this disease.

A New Pathway to Relief: Methotrexate for Probable Rheumatoid Arthritis

This study highlights the potential of MTX as a treatment option for patients with probable RA, suggesting that it can effectively delay the progression of the disease and potentially improve long-term outcomes.

A Desert Oasis of Hope: Managing Rheumatoid Arthritis

This research suggests that MTX could be a valuable tool for managing RA, potentially slowing down the progression of the disease and improving long-term outcomes for patients. It's like discovering a hidden oasis in the desert, offering a chance to regain control of their health and well-being.

Dr.Camel's Conclusion

This study investigates the effectiveness of methotrexate (MTX) in patients with probable RA, suggesting that MTX can effectively delay the diagnosis of RA and slow down the progression of joint damage, offering a potential benefit for patients with probable RA.

Date :
  1. Date Completed 2007-06-19
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

17469099

DOI: Digital Object Identifier

10.1002/art.22525

Related Literature

Article Analysis
・Effective treatment of arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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