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Selective serotonin reuptake inhibitor (SSRI) add-on therapy for the negative symptoms of schizophrenia: a meta-analysis.

Author: ElieRobert, PotvinStéphane, SepehryAmir Ali, StipEmmanuel

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The study discussed the potential for selective serotonin reuptake inhibitor (SSRI) augmentation therapy to provide greater relief of negative symptoms in schizophrenia, noting conflicting results from published studies.
Paper Details　
Original Abstract of the Article :
Negative symptoms are among the most chronic symptoms of schizophrenia. Even with the advent of atypical antipsychotic drugs, negative symptoms remain mostly refractory to treatment. It has been proposed that selective serotonin reuptake inhibitor (SSRI) augmentation therapy in schizophrenia could p...See full text at original site
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引用元：
https://doi.org/10.4088/jcp.v68n0417

データ提供：米国国立医学図書館（NLM）

Addressing the Shadows of Schizophrenia: A Meta-Analysis

[Negative symptoms] are a [common and debilitating] feature of [schizophrenia]. This [meta-analysis] explores the potential of [selective serotonin reuptake inhibitors (SSRIs)] as an [add-on therapy] for [negative symptoms] in [patients with schizophrenia]. The authors reviewed [published studies] to assess the [effectiveness] of [SSRIs] in [alleviating negative symptoms].

The Quest for Better Treatment

While [SSRIs] have shown [promise] in [treating negative symptoms], the [results] of [previous studies] have been [inconclusive]. This meta-analysis aimed to [synthesise] the existing [evidence] to [determine] whether [SSRIs] could be a [valuable addition] to [standard treatment] for [negative symptoms].

Illuminating the Shadows

Imagine a [desert] where [shadows] are [long] and [deep]. This meta-analysis aims to [shed light] on the [effectiveness] of [SSRIs] in [treating negative symptoms] of [schizophrenia]. It's like searching for a [hidden oasis] – the [quest] for [better treatment] is [ongoing].

Dr. Camel's Conclusion

This meta-analysis underscores the [ongoing need] for [effective treatments] for [negative symptoms] in [schizophrenia]. While [SSRIs] hold [potential] as an [add-on therapy], further [research] is needed to [clarify] their [efficacy] and [optimal usage]. It's like a [camel] that needs [guidance] to [navigate] the [shifting sands] of the [desert] – [more research] is needed to [guide] the [path] to [better treatments].

Date :
  1. Date Completed 2007-05-10
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

17474817

DOI: Digital Object Identifier

10.4088/jcp.v68n0417

Related Literature

Article Analysis
・Effective treatment of schizophrenia
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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