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The development of topically acting carbonic anhydrase inhibitors as anti-glaucoma agents.
Author: MincioneFrancesco, ScozzafavaAndrea, SupuranClaudiu T
Original Abstract of the Article :
Carbonic anhydrase inhibitors (CAIs) such as acetazolamide, methazolamide, ethoxzolamide and dichlorophenamide were and still are widely used systemic antiglaucoma drugs. Their mechanism of action consists in inhibition of CA isozymes present in ciliary processes of the eye (such as CA II, IV and XI...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2174/156802607780636735
データ提供:米国国立医学図書館(NLM)
Topical Carbonic Anhydrase Inhibitors: A New Era in Glaucoma Treatment
The field of [glaucoma] treatment is always seeking new and improved approaches to manage this chronic eye condition. This study explores the development of [topically acting carbonic anhydrase inhibitors (CAIs)] as a more targeted and effective treatment option. It's like finding a new oasis in the desert, a more precise and localized way to deliver hydration and relief.
The researchers discuss the limitations of traditional [systemic CAIs], which can cause undesirable side effects due to their systemic effects. They highlight the development of [topical CAIs], such as [dorzolamide] and [brinzolamide], which offer a more targeted approach to [glaucoma] treatment, minimizing side effects and improving patient compliance. It's like building a system of irrigation channels in the desert, delivering water directly to the targeted areas.
A Targeted Approach to Glaucoma Treatment
The study highlights the potential benefits of [topical CAIs], offering a more targeted and effective approach to [glaucoma] treatment. It's like using a precise watering can in the desert, ensuring that the water reaches the intended plants without wasting resources or causing damage to other areas.
A New Oasis for Glaucoma Patients
The development of [topical CAIs] represents a significant advance in [glaucoma] treatment, offering a more effective and well-tolerated option for patients. It's like discovering a new oasis in the desert, providing a much-needed source of relief and hope for those struggling with this chronic condition.
Dr. Camel's Conclusion
This study underscores the importance of developing targeted treatment options for [glaucoma]. The development of [topical CAIs] offers a new and potentially more effective way to manage this challenging condition, minimizing side effects and improving patient outcomes. It's like finding a more efficient and effective way to irrigate a desert, ensuring that the water reaches the intended plants and promotes healthy growth.
Date :
- Date Completed 2007-06-21
- Date Revised 2019-09-07
Further Info :
Related Literature
English
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