Paper Details

  1. Home
  2. Paper Details

Effectiveness of mood stabilizers and antipsychotics in the maintenance phase of bipolar disorder: a systematic review of randomized controlled trials.

Author: BellAngus, CorneliusVictoria, SmithLesley A, WarnockAdrian, YoungAllan H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Mood stabilizers like lithium, lamotrigine, olanzapine, and valproate semisodium have differing profiles of efficacy and tolerability, suggesting complementary roles in long-term maintenance treatment for bipolar disorder. Lithium and olanzapine were more effective in preventing manic relapses, while lamotrigine and valproate semisodium were more effective in preventing depressive relapses.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Bipolar disorder (BD) is a leading cause of disability. Systematic reviews of randomized trials for the treatment of the maintenance phase of BD are lacking. OBJECTIVES: To determine the efficacy and tolerability of mood stabilizers and antipsychotics in the maintenance treatment of BD....See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/j.1399-5618.2007.00490.x

データ提供：米国国立医学図書館（NLM）

A Camel's Journey: Navigating the Complexities of Bipolar Disorder Management

This research takes a deep dive into the world of bipolar disorder (BD), a chronic mental health condition characterized by alternating episodes of mania and depression. The study systematically reviews randomized controlled trials that investigated the efficacy and tolerability of various medications used to manage BD, focusing on the maintenance phase of treatment. The research highlights the effectiveness of lithium, lamotrigine, olanzapine, and valproate semisodium in preventing mood episodes and reducing relapse rates. This research offers valuable insights into the treatment options available for individuals with BD, helping clinicians tailor treatment plans to meet individual needs.

The Camel's Perspective: A Search for Stability in a Shifting Landscape

This research underscores the importance of finding effective treatments that provide stability for individuals living with bipolar disorder. The study's findings highlight the effectiveness of certain medications in reducing relapse rates and improving overall quality of life for those with BD. It emphasizes the need for careful consideration of medication options and ongoing monitoring to ensure optimal treatment outcomes.

The Camel's Perspective: A Search for Stability in a Shifting Landscape

This research reminds us that managing mental health conditions like bipolar disorder requires a multi-faceted approach, encompassing medication, therapy, and lifestyle interventions. It highlights the importance of collaborating with healthcare professionals and exploring different treatment options to find what works best for each individual. It's like the desert, where navigating shifting sands requires a combination of knowledge, experience, and adaptability.

Dr.Camel's Conclusion

This systematic review provides valuable insights into the effectiveness of mood stabilizers and antipsychotics in the maintenance treatment of bipolar disorder. The research suggests that lithium, lamotrigine, olanzapine, and valproate semisodium can effectively prevent relapses and improve long-term outcomes for individuals with BD.
Date :
  1. Date Completed 2007-10-15
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17547586

DOI: Digital Object Identifier

10.1111/j.1399-5618.2007.00490.x

Related Literature

Article Analysis
・Effective treatment of bipolar disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.