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[New generation antihistamines as monotherapy or in combination. What is the relevance for daily clinical routine for allergic rhinoconjunctivitis].

Author: KöberleinJ, MösgesR

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

The study discusses the use of ebastine, a non-sedating antihistamine, for the treatment of severe allergic rhinitis. While current guidelines recommend a combination of oral antihistamines and nasal steroids, many patients prefer antihistamine monotherapy. Ebastine, at a higher dose of 20 mg daily, has demonstrated improved clinical efficacy compared to the standard dose of 10 mg daily, without an increased risk of side effects.
Paper Details　
Original Abstract of the Article :
The guidelines of German and European associations of allergology recommend the treatment of severe allergic rhinitis with a combination of oral antihistamines and nasal steroids. Many patients face this option rather skeptically, so that ENT specialists mostly use antihistamine monotherapy with a h...See full text at original site
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引用元：
https://doi.org/10.1007/s00106-006-1509-1

データ提供：米国国立医学図書館（NLM）

Antihistamines for Allergic Rhinitis: Navigating the Desert of Treatment Options

Allergic rhinitis, a common ailment, can significantly impact quality of life. This study examines the effectiveness of new generation antihistamines in treating allergic rhinitis, evaluating their use as monotherapy and in combination with nasal steroids. The authors highlight the potential benefits and limitations of different treatment approaches, emphasizing the importance of individualized care.

Finding the Right Oasis in the Desert of Allergic Rhinitis: A Personalized Approach to Treatment

This research offers valuable insights into the treatment of allergic rhinitis, emphasizing the importance of personalized care. The authors' findings suggest that new generation antihistamines can be effective both as monotherapy and in combination with nasal steroids, providing healthcare providers with a range of treatment options to tailor to individual patient needs.

Navigating the Desert of Side Effects: Choosing the Right Path

The study's findings underscore the need for careful consideration of potential side effects when selecting antihistamine treatments. The authors' observations regarding drowsiness associated with certain antihistamines highlight the importance of weighing potential benefits against potential risks. This research emphasizes the importance of open communication between patients and their healthcare providers to determine the best course of treatment.

Dr.Camel's Conclusion

This study provides a valuable roadmap for navigating the desert of allergic rhinitis treatment. The authors' findings highlight the effectiveness of new generation antihistamines and the importance of tailoring treatment approaches to individual patient needs. By carefully weighing potential benefits and risks, healthcare providers can help patients find the right oasis in the desert of allergic rhinitis.

Date :
  1. Date Completed 2007-07-10
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

17566806

DOI: Digital Object Identifier

10.1007/s00106-006-1509-1

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Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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