In vitro activity of orally administered antimicrobial agents against Haemophilus influenzae recovered from children monitored longitudinally in a group day-care center.

Author: GeorgeM J, GilliganP H, HendersonF W, KitchB

Paper Details 
Original Abstract of the Article :
To determine whether the prevalence of resistance to commonly used oral antimicrobial agents varied over time, we compared the in vitro susceptibilities of 217 strains of Haemophilus influenzae recovered from nasopharyngeal secretions of children in a day-care center studied longitudinally between 1...See full text at original site
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引用元:
https://doi.org/10.1128/AAC.35.10.1960

データ提供:米国国立医学図書館(NLM)

Haemophilus influenzae in Day-Care Centers: Monitoring Antibiotic Resistance

Haemophilus influenzae, a common bacterial pathogen, can cause a range of infections, particularly in young children. Imagine a bustling desert oasis where a contagious illness can quickly spread among the inhabitants. This study, conducted within the field of microbiology, investigates the prevalence of antibiotic resistance in Haemophilus influenzae strains recovered from children in a group day-care center over an extended period. The study employed a longitudinal design, analyzing the in vitro susceptibility of 217 strains collected between 1979 and 1987. The researchers found that the overall rate of beta-lactamase production remained relatively stable over time, suggesting that antibiotic resistance patterns were not significantly changing. The study also evaluated the susceptibility of the strains to various oral antimicrobial agents, providing valuable insights into the effectiveness of different antibiotics in treating Haemophilus influenzae infections.

Understanding Antibiotic Resistance Patterns

The study's findings provide insights into the dynamics of antibiotic resistance in Haemophilus influenzae. Just as a desert landscape can shift over time due to erosion or changing weather patterns, antibiotic resistance patterns can also evolve due to factors such as overuse and misuse of antibiotics. Monitoring these patterns is crucial for ensuring that effective treatment options remain available.

Treating Haemophilus influenzae Infections: Effective Antibiotic Therapy

The study highlights the importance of appropriate antibiotic therapy for Haemophilus influenzae infections. While the study found that certain antibiotics were effective in inhibiting the majority of strains, it emphasizes the need for careful selection of antibiotics based on susceptibility testing to ensure optimal treatment outcomes.

Dr.Camel's Conclusion

Like a desert traveler navigating a shifting landscape, healthcare professionals must constantly adapt to the evolving dynamics of antibiotic resistance. This study underscores the importance of ongoing monitoring and research to ensure the effectiveness of antibiotic therapy for Haemophilus influenzae infections.

Date :
  1. Date Completed 1992-01-31
  2. Date Revised 2021-05-26
Further Info :

Pubmed ID

1759814

DOI: Digital Object Identifier

10.1128/AAC.35.10.1960

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SNS
PICO Info
in preparation
Languages

English

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