Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma.

Author: GibsonP G, IrvingL B, KohM S, LassersonT J, TeeA K H, WilsonA J

Paper Details 
Original Abstract of the Article :
BACKGROUND: Theophylline and long acting beta-2 agonists are bronchodilators used for the management of persistent asthma symptoms, especially nocturnal asthma. They represent different classes of drug with differing side-effect profiles. OBJECTIVES: To assess the comparative efficacy, safety and s...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406469/

データ提供:米国国立医学図書館(NLM)

The Quest for Optimal Asthma Management: A Tale of Two Bronchodilators

Asthma research is a constant quest for effective treatments, much like a thirsty traveler searching for an oasis in a desert. This study compares the efficacy and safety of two widely used bronchodilators, theophylline and long-acting beta-2 agonists, in managing persistent asthma symptoms, especially nocturnal asthma. The study aimed to uncover the best approach to combatting the challenges of asthma by comparing these two different drug classes.

Long-Acting Beta-2 Agonists: A Promising Path to Asthma Relief

The study found that long-acting beta-2 agonists, particularly salmeterol, were more effective than theophylline in improving morning and evening peak expiratory flow (PEF) and reducing the need for rescue medications. Salmeterol was also associated with fewer adverse events compared to theophylline. These findings indicate that long-acting beta-2 agonists may offer a more effective and well-tolerated option for managing asthma in adults and adolescents.

Asthma Management: A Collaborative Effort

The results of this study highlight the importance of working closely with healthcare professionals to determine the best asthma management strategy. By understanding the potential benefits and risks of different treatment options, individuals with asthma can take an active role in managing their condition and achieving better control over their symptoms.

Dr. Camel's Conclusion

This study is like a compass guiding us through the desert of asthma research. It reveals the effectiveness of long-acting beta-2 agonists, particularly salmeterol, for managing persistent asthma symptoms, especially nocturnal asthma. While theophylline remains a viable option, the study suggests that long-acting beta-2 agonists may provide a more effective and well-tolerated approach for many patients.

Date :
  1. Date Completed 2007-10-18
  2. Date Revised 2021-09-03
Further Info :

Pubmed ID

17636663

DOI: Digital Object Identifier

PMC8406469

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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