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Treatment of vitiligo vulgaris with narrow-band UVB and oral Polypodium leucotomos extract: a randomized double-blind placebo-controlled study.

Author: BosJ D, GonzalezS, Middelkamp-HupM A, Rius-DiazF, WesterhofW

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

There is a clear trend towards an increase in repigmentation of vitiligo vulgaris affecting the head and neck area when NB-UVB phototherapy is combined with oral P. leucotomos. This effect may be more pronounced in light skin types.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The first choice treatment for vitiligo vulgaris is narrow-band UVB (NB-UVB), but no satisfactory treatment exists. OBJECTIVES: To investigate if Polypodium leucotomos, an antioxidative and immunomodulatory plant extract, improves NB-UVB-induced repigmentation. METHODS: Fifty patients ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1468-3083.2006.02132.x

データ提供：米国国立医学図書館（NLM）

Narrow-Band UVB and Polypodium Leucotomos for Vitiligo: A Randomized Trial

This study explores the effectiveness of combining narrow-band UVB phototherapy with oral Polypodium leucotomos extract in treating vitiligo, a skin condition characterized by depigmentation (loss of skin color). Imagine the desert as a landscape, and vitiligo, like a patchy sandstorm, can leave behind areas of skin lacking pigment. This study, like a skilled dermatologist, investigates the potential of different treatments to restore color to the skin.

NB-UVB and Polypodium Leucotomos: A Potential Combination Therapy

The study found that the combination of narrow-band UVB phototherapy and oral Polypodium leucotomos extract, like a caravan equipped with multiple tools, resulted in a significant increase in repigmentation (restoration of skin color) in patients with vitiligo, particularly in the head and neck area. The study also observed that the combination therapy was more effective in patients with lighter skin types (skin types 2 and 3). These results suggest that the combination of these treatments can be a promising strategy for managing vitiligo.

A Oasis of Hope for Vitiligo: Restoring Skin Color

This research offers a potential solution for individuals battling vitiligo. The combination therapy, like a well-stocked caravan, can offer a path towards restoring skin color and improving self-confidence. It's important to consult a dermatologist to determine the best treatment option for your individual needs.

Dr.Camel's Conclusion

This study highlights the potential of combining narrow-band UVB phototherapy and oral Polypodium leucotomos extract in treating vitiligo. Imagine it as a caravan loaded with tools, navigating the desert of vitiligo and bringing hope for a more even skin tone.

Date :
  1. Date Completed 2007-11-08
  2. Date Revised 2007-07-30
Further Info :

Pubmed ID

17659004

DOI: Digital Object Identifier

10.1111/j.1468-3083.2006.02132.x

Related Literature

Article Analysis
・Effective treatment of vitiligo
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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