Infliximab inhibits progression of radiographic damage in patients with active psoriatic arthritis through one year of treatment: Results from the induction and maintenance psoriatic arthritis clinical trial 2.

Author: AntoniC, BeutlerA, BirbaraC, DooleyL T, GeusensP, GladmanD D, GuzzoC, HalterD, KavanaughA, KruegerG G, ZhouB, de VlamK, van der HeijdeD

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the effect of infliximab on progression of structural damage over 1 year in patients with active psoriatic arthritis (PsA) enrolled in the Induction and Maintenance Psoriatic Arthritis Clinical Trial 2. METHODS: In this double-blind, placebo-controlled study, 200 patients wit...See full text at original site
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引用元:
https://doi.org/10.1002/art.22805

データ提供:米国国立医学図書館(NLM)

Infliximab: A Protective Oasis in the Desert of Psoriatic Arthritis

Psoriatic arthritis (PsA), like a relentless desert storm, can wreak havoc on the body's joints, causing pain, inflammation, and even irreversible damage. This study investigates the long-term effects of infliximab, a powerful anti-inflammatory drug, on the progression of structural damage in patients with PsA.

The authors conducted a double-blind, placebo-controlled study, following patients over a year. Their findings reveal that infliximab, like a protective oasis in a harsh desert environment, significantly inhibited radiographic progression in PsA, mitigating the damaging effects of this chronic disease.

Infliximab: A Beacon of Hope for Preserving Joint Health

The study demonstrates that infliximab, like a steady stream in a desert landscape, effectively slowed down the progression of joint damage in PsA, potentially preserving joint function and reducing the long-term impact of this debilitating disease.

Navigating the Desert of Chronic Inflammation: A Multifaceted Approach

While infliximab offers a beacon of hope, it is important to remember that PsA is a complex and multifaceted disease. A comprehensive approach to treatment, including medication, physical therapy, lifestyle modifications, and ongoing monitoring, is essential for navigating this challenging landscape. Like a well-prepared desert traveler, patients should work closely with their healthcare providers to develop a personalized plan that meets their individual needs and promotes optimal long-term health.

Dr.Camel's Conclusion

This study underscores the importance of early intervention and proactive management of PsA. Infliximab, with its ability to protect joint health, offers a valuable tool for navigating this challenging disease. As we continue to journey through the desert of medical research, we must strive to develop more effective and personalized approaches, ensuring that all those affected by PsA have access to the best possible care.

Date :
  1. Date Completed 2007-09-18
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

17665424

DOI: Digital Object Identifier

10.1002/art.22805

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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