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Perioperative desmopressin prolongs survival in surgically treated bitches with mammary gland tumours: a pilot study.

Author: AlonsoDaniel F, GobelloCristina, GomezDaniel E, HermoGuillermo A, RipollGiselle V, ScursoniAlejandra M, TorresPerla

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Desmopressin, a medication used to treat bleeding disorders, has been shown to inhibit tumor metastasis in mice. This study found that desmopressin, when given perioperatively to dogs with mammary gland tumors, improved disease-free period and overall survival time.
Paper Details　
Original Abstract of the Article :
Desmopressin (1-deamino-8-d-arginine vasopressin, also known as DDAVP) is a safe haemostatic compound capable of inhibiting lymph node and lung metastasis in a mouse model of mammary tumour manipulation and surgical excision. The aim of this study was to test the efficacy and safety of perioperative...See full text at original site
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引用元：
https://doi.org/10.1016/j.tvjl.2007.06.015

データ提供：米国国立医学図書館（NLM）

Perioperative Desmopressin: A Potential Game-Changer for Canine Mammary Tumors

This pilot study investigates the use of [desmopressin], a synthetic hormone, in treating [mammary gland tumors (MGT)] in dogs. The authors explored the efficacy and safety of perioperative desmopressin in bitches with stage III or IV MGT undergoing surgical removal. They found that desmopressin significantly prolonged both disease-free and overall survival time, suggesting a potential benefit as an adjuvant therapy.

Desmopressin: A Promising New Ally in the Fight Against Canine Cancer

This study offers a glimmer of hope for canine cancer patients. Desmopressin, a medication commonly used for other purposes, has shown potential as an adjuvant therapy for dogs with mammary tumors. It's like discovering a hidden oasis in a vast and unforgiving desert, providing a source of relief and potentially prolonging survival. The authors' findings warrant further research to validate the efficacy and safety of desmopressin in canine cancer treatment.

Towards Personalized Cancer Treatment for Our Canine Companions

This study emphasizes the need for innovative approaches in veterinary oncology. Desmopressin's potential to improve survival outcomes in dogs with MGT highlights the importance of exploring new therapies and personalized treatment strategies. Just as a desert traveler adapts to the terrain, veterinarians must continually adapt their approaches to provide the best possible care for their animal patients.

Dr. Camel's Conclusion

This pilot study suggests that desmopressin might offer a promising new treatment option for dogs with mammary tumors. The findings indicate that desmopressin could potentially improve survival outcomes, acting as an adjuvant therapy alongside surgery. It's like finding a hidden oasis in a vast and unforgiving desert, offering a source of relief. Further research is needed to confirm these findings and investigate the optimal use of desmopressin in canine cancer treatment.
Date :
  1. Date Completed 2008-11-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17719812

DOI: Digital Object Identifier

10.1016/j.tvjl.2007.06.015

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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