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Meta-analysis: enteral nutrition in active Crohn's disease in children.
Author: DziechciarzP, HorvathA, ShamirR, SzajewskaH
Original Abstract of the Article :
BACKGROUND: Controversy exists surrounding the optimal treatment for inducing remission in active Crohn's disease. AIM: To review and update evidence on the effectiveness of enteral nutrition (EN) in treating active Crohn's disease in children. METHODS: MEDLINE, EMBASE and The Cochrane Library (up...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2036.2007.03431.x
データ提供:米国国立医学図書館(NLM)
Enteral Nutrition: A Promising Option for Crohn's Disease in Children?
The world of pediatric gastroenterology is constantly evolving, and one area of ongoing research is the treatment of Crohn's disease, a chronic inflammatory bowel disease. Enteral nutrition (EN), which involves receiving nutrients through a tube into the stomach or small intestine, is a potential therapeutic approach for this condition. This study delves into the effectiveness of EN in treating active Crohn's disease in children. The researchers conducted a comprehensive review of randomized controlled trials (RCTs), comparing EN to corticosteroid therapy and various EN regimens. While some studies suggested similar efficacy between EN and corticosteroids, the limited data and large sample sizes needed for conclusive results highlight the necessity for further research.
Enteral Nutrition: A Potential Alternative to Corticosteroids
This research suggests that EN may be just as effective as corticosteroids in inducing remission in children with Crohn's disease. The researchers found no significant difference in remission rates between the two groups when comparing EN and corticosteroid therapy. This finding is promising, especially considering the potential side effects associated with corticosteroids, such as bone thinning and weight gain. However, the authors emphasize the need for larger studies to confirm these findings and provide more definitive answers.
Enteral Nutrition: More Research Needed to Ensure Safety and Effectiveness
While the potential for EN as a safe and effective treatment for Crohn's disease in children is exciting, this study underscores the importance of continued research. More robust studies are needed to gather data on long-term outcomes, including growth and quality of life, to fully assess the benefits and risks of this approach. The study also highlights the need for further investigation into optimal EN regimens for specific patient populations. As a researcher, I am fascinated by the potential of EN to improve the lives of children with Crohn's disease, and I eagerly await the results of future studies.
Dr.Camel's Conclusion
This study suggests that enteral nutrition could be a promising alternative to corticosteroids in treating Crohn's disease in children, but more research is needed to confirm its effectiveness and safety. Just like a camel navigating a vast desert, we must carefully consider the implications of each step in our journey toward understanding the complex world of Crohn's disease.
Date :
- Date Completed 2007-12-14
- Date Revised 2022-04-09
Further Info :
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