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The use of colesevelam hydrochloride in the treatment of dyslipidemia: a review.

Author: DavidsonMichael H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Colesevelam hydrochloride is a non-absorbed lipid-lowering agent used to reduce LDL-C in patients with primary hypercholesterolemia. It is preferred over other bile-acid sequestrants due to fewer gastrointestinal side effects and can be used as monotherapy or in combination with other cholesterol-lowering drugs.
Paper Details　
Original Abstract of the Article :
Bile-acid sequestrants augment cholesterol excretion via enhanced conversion to bile acids, and act to lower low-density lipoprotein cholesterol (LDL-C), especially when combined with other cholesterol-lowering drugs. Colesevelam hydrochloride (HCL) has become the preferred drug of this class due to...See full text at original site
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引用元：
https://doi.org/10.1517/14656566.8.15.2569

データ提供：米国国立医学図書館（NLM）

Colesevelam Hydrochloride: A New Avenue for Dyslipidemia Management

Dyslipidemia, a condition characterized by abnormal levels of lipids in the blood, is a significant risk factor for cardiovascular disease. This research delves into the therapeutic potential of colesevelam hydrochloride (HCL), a bile-acid sequestrant, in the management of dyslipidemia. The study explores the efficacy and safety of colesevelam HCL, highlighting its role in lowering LDL-cholesterol levels, particularly when used in combination with other cholesterol-lowering drugs.

Colesevelam HCL: A Promising Option for Dyslipidemia Management

The study demonstrates that colesevelam HCL is a well-tolerated and effective treatment option for patients with dyslipidemia. Its ability to lower LDL-cholesterol levels, especially when used in combination with other medications, makes it a valuable tool for managing this condition and reducing cardiovascular risk. This study sheds light on the potential benefits of colesevelam HCL, suggesting that it could be a beneficial addition to the therapeutic arsenal for dyslipidemia management.

Optimizing Cholesterol Management

This research encourages healthcare providers to consider colesevelam HCL as a viable option for managing dyslipidemia. By utilizing this medication in combination with other cholesterol-lowering drugs, we can potentially achieve optimal cholesterol control and reduce the risk of cardiovascular disease.

Dr.Camel's Conclusion

Imagine a desert with a vast and complex ecosystem. Dyslipidemia, like a desert storm, can disrupt this delicate balance. Colesevelam HCL, like a sturdy camel caravan, helps to stabilize the ecosystem, lowering LDL-cholesterol levels and reducing the risk of cardiovascular disease. This research offers a valuable tool for navigating the complexities of dyslipidemia and promoting cardiovascular health.

Date :
  1. Date Completed 2007-12-06
  2. Date Revised 2019-09-17
Further Info :

Pubmed ID

17931091

DOI: Digital Object Identifier

10.1517/14656566.8.15.2569

SNS
PICO Info
in preparation
Languages

English

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