Side Effects of colestipol: A Synthesis of Findings from 29 Studies

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Original Abstract of the Article

Major Research Findings

Colestipol is a bile acid sequestrant that is commonly used to treat high cholesterol. Several studies have shown that colestipol is effective and safe in treating high cholesterol. 6 , 14 , 4 , 19 , 24 , 5 , 15 , 13 , 20 , 9 , 27 , 7 , 18 , 8 , 10 , 17 , 28 , 3 , 11 , 16 , 22 , 23 , 21 , 2 , 26 , 12 , 1 Colestipol is recognized as an effective treatment for high cholesterol, but some side effects have been reported.

Reasons for Side Effects

Colestipol works by binding to bile acids in the gut, which prevents the absorption of cholesterol. This bile acid binding action is thought to be responsible for gastrointestinal side effects. In addition, colestipol may interfere with the absorption of other medications in the gut. 24

Common Side Effects

Constipation

Colestipol can cause constipation because it binds to bile acids and is excreted in the stool, making the stool harder. Constipation has been reported as a side effect. 24 , 19 , 28 , 8 , 16 , 15 , 23 , 13 , 6

Abdominal pain and discomfort

Colestipol can interfere with the function of the gastrointestinal tract. Therefore, gastrointestinal side effects such as abdominal pain and discomfort have been reported. 24 , 19 , 28 , 8 , 16 , 15 , 23 , 13 , 6

Diarrhea

Colestipol can stimulate bowel movements, so diarrhea has been reported as a side effect. 24 , 19 , 28 , 8 , 16 , 15 , 23 , 13 , 6

Nausea

Colestipol can interfere with the function of the stomach. Therefore, gastrointestinal side effects such as nausea have been reported. 24 , 19 , 28 , 8 , 16 , 15 , 23 , 13 , 6

Maldigestion

Colestipol may interfere with the function of digestive enzymes. Therefore, side effects such as maldigestion have been reported. 24 , 19 , 28 , 8 , 16 , 15 , 23 , 13 , 6

Liver function abnormalities

Colestipol can put stress on the liver. Therefore, side effects such as liver function abnormalities have been reported. 2

Vitamin deficiency

Colestipol can interfere with the absorption of nutrients such as vitamins. Therefore, side effects such as vitamin deficiency have been reported. 24

Drug interactions

Colestipol can interfere with the absorption of other medications. Therefore, caution is needed with drug interactions. 24

Side Effect Management

Constipation

Dietary and exercise therapy are effective in preventing constipation. In dietary therapy, it is important to consume foods rich in dietary fiber and drink plenty of fluids. In exercise therapy, engaging in light exercise as a habit can stimulate bowel function. 23 , 13

Abdominal pain and discomfort

If you experience symptoms such as abdominal pain or discomfort, stop taking colestipol and consult your doctor. 23 , 13

Diarrhea

If you experience diarrhea, consult your doctor. You may need to take antidiarrheal medication. 23 , 13

Nausea

If you experience nausea, try eating small meals slowly. Also, make sure to drink plenty of fluids. If symptoms do not improve, consult your doctor. 23 , 13

Maldigestion

If you experience maldigestion, try to eat foods that are easy to digest. It may also be helpful to reduce the amount of food you eat or increase the number of meals you eat. 23 , 13

Liver function abnormalities

If you experience symptoms of liver function abnormalities, stop taking colestipol and consult your doctor. 2

Vitamin deficiency

If you experience symptoms of vitamin deficiency, consult your doctor. You may need to take vitamin supplements. 24

Drug interactions

If you are taking other medications, consult your doctor. Colestipol can interfere with the absorption of other medications. 24

Comparison of Studies

Commonalities

Many studies have shown that colestipol is effective in treating high cholesterol. 6 , 14 , 4 , 19 , 24 , 5 , 15 , 13 , 20 , 9 , 27 , 7 , 18 , 8 , 10 , 17 , 28 , 3 , 11 , 16 , 22 , 23 , 21 , 2 , 26 , 12 , 1 Also, many studies have shown that colestipol is prone to causing gastrointestinal side effects. 24 , 19 , 28 , 8 , 16 , 15 , 23 , 13 , 6

Differences

Some studies have shown that colestipol can be more effective in lowering cholesterol when used in combination with other medications. 18 , 15 , 10 , 17 , 3 , 11 , 16 , 12 Also, studies have shown that colestipol can be effective even when used in low doses. 22 , 8 , 18 Some studies have shown that colestipol may affect liver function. 2

Precautions for Real-life Application

Colestipol is an effective treatment for high cholesterol, but it can cause gastrointestinal side effects. Therefore, when taking colestipol, follow your doctor's instructions and pay attention to side effects. Colestipol can interfere with the absorption of other medications. Therefore, consult your doctor if you are taking other medications. If you are concerned about colestipol side effects, consult your doctor to discuss other treatment options.

Limitations of Current Research

Long-term safety of colestipol has not been sufficiently studied yet. Also, the mechanisms of colestipol side effects are still not fully understood. Therefore, when taking colestipol, follow your doctor's instructions and be aware of side effects.

Future Research Directions

Further research on the long-term safety and mechanisms of colestipol side effects is needed. The development of new treatment methods to enhance the effects of colestipol is also expected.

Conclusion

Colestipol is an effective drug for treating high cholesterol, but it can cause gastrointestinal side effects. Therefore, when taking colestipol, follow your doctor's instructions and pay attention to side effects. If you are concerned about colestipol side effects, consult your doctor to discuss other treatment options. Further research on the long-term safety and mechanisms of colestipol side effects is needed.

Keywords
Benefit Keywords
Phosphate binding
1
None mentioned
2
Acceptability improvement
Compliance improvement
Lipid lowering
3
Dyslipidemia treatment
LDL-C reduction
4
Colestipol tablets
Hypercholesterolaemia
5
Improved lipid profile
Lower cholesterol
6
Cholesterol lowering
Improved cholesterol
7
Increase HDL cholesterol
Lower LDL cholesterol
8
Increased HDL cholesterol
Reduced LDL cholesterol
Reduced serum triglyceride
9
Increased HDL cholesterol
Reduced LDL cholesterol
Reduced triglycerides
10
Increased HDL cholesterol
Reduced cholesterol
Reduced triglycerides
11
Cholesterol lowering
Cost-effective
Well tolerated
12
Atherosclerosis retardation
Coronary event reduction
LDL cholesterol reduction
Safe and effective
13
Hypercholesterolaemia treatment
Hyperlipoproteinaemia treatment
14
Prevent new lesions
Stabilize lesions
15
Hypocholesterolemic effects
16
Lowers cholesterol
17
Reduces LDL cholesterol
Reduces high-density lipoprotein
Reduces very low density lipoprotein
18
Lower LDL cholesterol
Reduced side effects
19
Reduced diarrhea
20
Lipid lowering
21
Few side effects
Treats hypercholesterolemia
22
Reduces serum cholesterol
23
Improved compliance
Lower cholesterol
24
Atherogenic risk reduction
HDL increase
25
Low side effects
Lower cholesterol
26
Lowers LDL cholesterol
27
Lower LDL
Lower cholesterol
28
Lowers cholesterol
Prevents heart disease
29
Risk Keywords
Hepatotoxicity
2
Gastrointestinal side effects
4
Side effects
7
Incomplete treatment
Side effects
8
Flushing reaction
9
Increased liver enzymes
Weight gain
10
Increased liver enzymes
11
None reported
12
Side effects
13
Gastrointestinal symptoms
Headache
Joint stiffness
15
Gastrointestinal side effects
16
None reported
17
Constipation
Diarrhea
18
Increased LDL:HDL ratio
Lower HDL cholesterol
19
Abdominal cramps
Nausea
Vomiting
20
Serious side effects
21
Constipation
Gastrointestinal complaints
Increased triglyceride levels
23
Drug interactions
Gastrointestinal side effects
24
Side effects
25
Constipation
Gastrointestinal discomfort
27
Gastrointestinal problems
28
Side effects
29
Literature analysis of 29 papers
Positive Content
26
Neutral Content
1
Negative Content
2
Article Type
5
0
0
5
29
1.

Feasibility study of colestipol as an oral phosphate binder in hemodialysis patients.

Author: HoodChristopher J, WolleyMartin J, KamAngela L, Kendrik-JonesJamie C, MarshallMark R

Phosphate binding

This study examined the phosphate-binding effects of colestipol, a bile acid sequestrant. The study aimed to assess colestipol's potential as a phosphate binder, considering the limitations of current calcium- and aluminium-based binders, and its potential cost-effectiveness.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

2.

Colestipol-induced hepatotoxicity.

Author: SirmansS M, BeckJ K, BanhH L, FreemanD A

None mentioned
Hepatotoxicity

A 65-year-old man with type IIa dyslipidemia who received flavored colestipol granules 2 scoops/day for 3 months developed asymptomatic hepatotoxicity. Several of his liver enzymes were elevated 10 times the upper limit of normal. One week after discontinuing colestipol, serum transaminases fell dramatically, with some returning to normal limits. Four weeks after colestipol was discontinued, all liver function tests were normal.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

3.

A randomized crossover trial of combination pharmacologic therapy in children with familial hyperlipidemia.

Author: McCrindleBrian W, HeldenElizabeth, Cullen-DeanGeraldine, ConnerWilliam T

Acceptability improvement
Compliance improvement
Lipid lowering

This study compares the effectiveness and acceptability of a low-dose combination of colestipol and pravastatin versus a higher dose of colestipol alone in children with hyperlipidemia. The combination therapy shows better acceptability and lipid-lowering effects, with similar compliance and safety profiles.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

4.

The use of colesevelam hydrochloride in the treatment of dyslipidemia: a review.

Author: DavidsonMichael H

Dyslipidemia treatment
LDL-C reduction
Gastrointestinal side effects

Colesevelam hydrochloride is a non-absorbed lipid-lowering agent used to reduce LDL-C in patients with primary hypercholesterolemia. It is preferred over other bile-acid sequestrants due to fewer gastrointestinal side effects and can be used as monotherapy or in combination with other cholesterol-lowering drugs.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

5.

Colestipol tablets in adolescents with familial hypercholesterolaemia.

Author: TonstadS, OseL

Colestipol tablets
Hypercholesterolaemia

Colestipol tablets were safe and effective, and preferred by adolescents.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

6.

A randomized pilot trial of low-dose combination lipid-lowering therapy following coronary artery bypass grafting.

Author: BarbirM, HuntB J, GallowayD, TaylorA, IlsleyC, MitchellA, YacoubM

Improved lipid profile
Lower cholesterol

This study found that low-dose combinations of colestipol and simvastatin or colestipol and bezafibrate were effective and well tolerated in the management of moderate hyperlipidemia in patients who had undergone coronary artery bypass grafting.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

7.

Successful management of primary hypercholesterolaemia with simvastatin and low-dose colestipol.

Author: SimonsL A, SimonsJ, ParfittA

Cholesterol lowering
Improved cholesterol
Side effects

Combining a low dose of colestipol with simvastatin was more effective in reducing serum and LDL cholesterol levels than simvastatin alone.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

8.

[Small doses of the resin Colestid in the treatment of hyperlipoproteinemia].

Author: VálekJ, JirkovskáA, GrafnetterD

Increase HDL cholesterol
Lower LDL cholesterol
Incomplete treatment
Side effects

Colestid effectively reduced cholesterol levels in hypercholesterolaemic patients, with minimal side effects.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Czech

9.

Comparison of cholesterol-lowering regimens.

Author: SnyderS

Increased HDL cholesterol
Reduced LDL cholesterol
Reduced serum triglyceride
Flushing reaction

Lovastatin is a safe and effective treatment for hypercholesterolemia. Other drugs, such as cholestyramine, colestipol, gemfibrozil, nicotinic acid, and probucol, can also be used to treat hypercholesterolemia.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

11.

The effects of simvastatin on serum lipoproteins in severe hypercholesterolaemia.

Author: MolM J, StuytP M, DemackerP N, StalenhoefA F

Increased HDL cholesterol
Reduced cholesterol
Reduced triglycerides
Increased liver enzymes

Simvastatin effectively reduced serum cholesterol levels in patients with hypercholesterolaemia, with minimal side effects.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

13.

Review of clinical studies of bile acid sequestrants for lowering plasma lipid levels.

Author: LaRosaJ

Atherosclerosis retardation
Coronary event reduction
LDL cholesterol reduction
Safe and effective
Side effects

Bile acid sequestrants cholestyramine and colestipol are effective in lowering circulating low-density lipoprotein (LDL) cholesterol levels. They have been shown to lower the incidence of new coronary events and retard the progression of coronary atherosclerosis. They are generally well tolerated, and side effects can be managed by lowering the dosage.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

15.

Effects of combined probucol-colestipol treatment for familial hypercholesterolemia and coronary artery disease.

Author: KuoP T, WilsonA C, KostisJ B, MoreyraA E

Prevent new lesions
Stabilize lesions
Gastrointestinal symptoms
Headache
Joint stiffness

Combined probucol-colestipol therapy plus diet was effective in treating familial hypercholesterolemia and coronary artery disease. The combination therapy stabilized the progression of existing lesions and prevented the formation of new lesions.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

16.

Controlled studies of the efficacy and safety of combined probucol-colestipol therapy.

Author: DujovneC A, KrehbielP, ChernoffS B

Hypocholesterolemic effects
Gastrointestinal side effects

Combined probucol-colestipol therapy was more effective in lowering LDL cholesterol levels than either drug alone in hypercholesterolemic patients. The combination therapy was also well tolerated and significantly reduced the gastrointestinal side effects of either drug used alone.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

17.

Mevinolin plus colestipol in therapy for severe heterozygous familial hypercholesterolemia.

Author: IllingworthD R

Lowers cholesterol
None reported

Mevinolin, a specific inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, effectively reduced serum cholesterol levels in 12 patients with severe heterozygous familial hypercholesterolemia. No consistent side effects were noted in up to 24 months of therapy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

18.

Low-dose colestipol plus probucol for hypercholesterolemia.

Author: DujovneC A, ChernoffS B, KrehbielP, JacksonB, DeCourseyS, TaylorH

Reduces LDL cholesterol
Reduces high-density lipoprotein
Reduces very low density lipoprotein
Constipation
Diarrhea

Combining colestipol and probucol reduced LDL cholesterol more effectively than colestipol alone, with a 50% reduction in colestipol dosage resulting in similar efficacy and improved tolerability.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

19.

Probucol with colestipol in the treatment of hypercholesterolemia.

Author: DujovneC A, KrehbielP, DecourseyS, JacksonB, ChernoffS B, PittermanA, GartyM

Lower LDL cholesterol
Reduced side effects
Increased LDL:HDL ratio
Lower HDL cholesterol

Probucol and colestipol combined were more effective in reducing LDL cholesterol levels than either drug alone, with fewer side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

20.

Colestipol hydrochloride prophylaxis of diarrhea during pelvic radiotherapy.

Author: StrykerJ A, ChungC K, LayserJ D

Reduced diarrhea
Abdominal cramps
Nausea
Vomiting

Colestipol hydrochloride was not effective in preventing radiation-induced diarrhea due to its side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

22.

"Low dose" colestipol in children, adolescents and young adults with familial hypercholesterolemia.

Author: SchlierfG, MrozikK, HeuckC C, MiddelhoffG, OsterP, RiesenW, SchellenbergB

Few side effects
Treats hypercholesterolemia

Colestipol, a bile acid sequestrant, was found to be effective in lowering plasma cholesterol levels in children, adolescents, and young adults with familial hypercholesterolemia. In a study involving 11 patients, colestipol significantly reduced total cholesterol and LDL cholesterol, while increasing HDL cholesterol.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

24.

Colestipol: a review of its pharmacological properties and therapeutic efficacy in patients with hypercholesterolaemia.

Author: HeelR C, BrogdenR N, PakesG E, SpeightT M, AveryG S

Improved compliance
Lower cholesterol
Drug interactions
Gastrointestinal side effects

Colestipol is effective in lowering cholesterol in patients with primary hypercholesterolaemia. The most common side effects are gastrointestinal in nature.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

25.

[Antilipemic agents available after the ban on clofibrate: clinical-pharmacological view].

Author: MertzD P

Atherogenic risk reduction
HDL increase
Side effects

Clofibrate-related substances, d-thyroxine, and nicotinic acid are the only hypolipidemic agents that lower serum lipid values while increasing HDL, a protective factor against atherosclerosis. There are differences in side effects among these agents.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : German

27.

Abnormal low density lipoproteins in children with familial hypercholesterolemia--effect of polyanion exchange resins.

Author: MordasiniR, TwelsiekF, OsterP, SchellenbergB, RaetzerH, HeuckC C, SchlierfG

Lowers LDL cholesterol
Constipation
Gastrointestinal discomfort

Polyanion exchange resins were used to treat 20 children and adolescents with familial Type IIa hyperlipoproteinemia. The most common side effects were gastrointestinal discomfort and constipation. The resins reduced total and LDL cholesterol and Apo-B, but did not alter the abnormal LDL composition. HDL cholesterol remained low during treatment.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

28.

[A comparative study of colestipol and colestyramine in children and adolescents with familial hypercholesterolaemia (author's transl)].

Author: MordasiniR, TwelsickF, OsterP, SchellenbergB, RaetzerH, HeuckC C, SchlierfG

Lower LDL
Lower cholesterol
Gastrointestinal problems

Colestyramine and colestipol were found to be effective in lowering cholesterol levels in children and adolescents with familial hypercholesterolemia, but did not affect triglyceride or phospholipid levels.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : German

29.

[Drug treatment of primary hyperlipoproteinemia (author's transl)].

Author: KloseG, MordasiniR, MiddelhoffG, AugustinJ, GretenH

Lowers cholesterol
Prevents heart disease
Side effects

Elevated serum lipids were found to contribute to the development of atherosclerosis, making it important to control lipid levels through dietary and pharmacological interventions.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : German

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