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Surgical implantation of steroids with antiangiogenic characteristics for treating neovascular age-related macular degeneration.

Author: GeltzerA, TuralbaA, VedulaS S

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review found that intravitreal triamcinolone injection for neovascular AMD does not appear to prevent severe vision loss and is associated with increased IOP and higher risk of cataract formation. Anecortave acetate 15 mg may have a mild benefit in stabilizing vision, but further better quality evidence is needed.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Neovascular age-related macular degeneration (AMD) is associated with rapid vision loss due to choroidal neovascularization (CNV), leakage, and scarring. Steroids have gained attention in their role for the treatment of neovascular AMD for their antiangiogenic and anti-inflammatory prope...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/17943833

データ提供：米国国立医学図書館（NLM）

Age-Related Macular Degeneration: A Desert of Vision Loss

Age-related macular degeneration (AMD) is a leading cause of vision loss in older adults. This research explores the potential benefits and risks of using steroids to treat neovascular AMD, a type of AMD that involves the growth of new blood vessels in the eye. They reviewed clinical trials evaluating the use of steroids with antiangiogenic properties. The results suggest that some steroids may have a stabilizing effect on vision, but more research is needed to determine their long-term safety and effectiveness. This study highlights the ongoing search for effective treatments for AMD, a condition that significantly impacts the lives of millions.

Steroids: A Potential Weapon in the Fight Against AMD

This research suggests that steroids with antiangiogenic properties may have potential benefits in treating neovascular AMD, potentially slowing down vision loss. It's like finding a hidden oasis in the desert of AMD, offering a glimmer of hope for preserving vision. However, more research is needed to determine the long-term safety and effectiveness of these medications.

Living Well With AMD

This research is a reminder that AMD is a complex condition, and that there is no one-size-fits-all treatment. It's essential to work with your doctor to determine the best approach for managing your AMD and maintaining your vision. This study highlights the ongoing search for new and effective treatments for this debilitating condition.

Dr.Camel's Conclusion

This research explores the potential benefits and risks of using steroids to treat AMD, a condition that can significantly impact the lives of millions. It's a reminder that the quest for new and effective treatments for AMD is an ongoing journey, and that finding solutions requires a careful balance of benefits and risks.

Date :
  1. Date Completed 2008-01-17
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

17943833

DOI: Digital Object Identifier

NIHMS644973

Related Literature

Article Analysis
・Effective treatment of macular degeneration
SNS
PICO Info
in preparation
Languages

English

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