Effects of rivastigmine on tremor and other motor symptoms in patients with Parkinson's disease dementia: a retrospective analysis of a double-blind trial and an open-label extension.

Author: De DeynPeter Paul, EmreMurat, HsuChuanchieh, KirschCourtney, LaneRoger, OertelWolfgang, PoeweWerner, TekinSibel, WoltersErik

Paper Details 
Original Abstract of the Article :
Rivastigmine is now widely approved for the treatment of mild to moderately severe dementia in Parkinson's disease (PDD). However, since anticholinergic drugs have a role in the management of tremor in patients with Parkinson's disease (PD), concerns have been raised that the use of cholinergic drug...See full text at original site
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引用元:
https://doi.org/10.2165/00002018-200831010-00007

データ提供:米国国立医学図書館(NLM)

Rivastigmine for Parkinson's Disease Dementia: A Quest for Balance

The world of neurodegenerative diseases is a labyrinthine desert, and Parkinson's disease dementia (PDD) presents a particularly challenging path. This research focuses on the potential benefits and risks of using rivastigmine, a medication commonly used to treat dementia, in patients with PDD. The researchers aimed to explore whether rivastigmine could affect tremor and other motor symptoms in patients with PDD.

Navigating a Complex Landscape: A Balancing Act

The study found that rivastigmine, while effective in treating cognitive symptoms, did not worsen tremor or other motor symptoms in PDD patients. This is akin to finding an oasis in the desert that not only provides water but also doesn't trigger a sandstorm. The researchers suggest that rivastigmine can be a valuable treatment option for PDD, balancing the need to manage cognitive decline with the potential for motor symptom improvement.

A Journey of Discovery: Finding the Right Path

The research highlights the importance of considering the overall impact of medications on patients with PDD, akin to navigating a desert landscape where both the destination and the journey are important. This study suggests that rivastigmine may provide a safe and effective treatment option for PDD, balancing the need to address cognitive decline with the potential for improving motor symptoms.

Dr.Camel's Conclusion

This research adds a new layer to our understanding of PDD treatment. The findings suggest that rivastigmine, while primarily targeting cognitive symptoms, can be a valuable tool for managing both cognitive and motor aspects of the disease. This is like discovering a hidden oasis in the desert, providing not only water but also protection from the harsh elements.

Date :
  1. Date Completed 2008-05-05
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18095748

DOI: Digital Object Identifier

10.2165/00002018-200831010-00007

SNS
PICO Info
in preparation
Languages

English

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