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Comparison of the efficacy and tolerability of pitavastatin and atorvastatin: an 8-week, multicenter, randomized, open-label, dose-titration study in Korean patients with hypercholesterolemia.

Author: AhnTae Hoon, ChaKwang-Soo, ChoiSi-Wan, ChungNamsik, HanSeong Wook, Ho YunKyeong, HyonMin Su, KimChee Jeong, KimDoo-Il, KimHyun Seung, KimWon Ho, KwanJun, LeeSang Hak, ParkSi Hoon, SeoHong Seog, ShimWan-Joo, ShinDong Gu, ShinYung Woo, YoonMyeong-Ho

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Pitavastatin and Atorvastatin were found to be equally effective and well tolerated in lowering LDL-C levels in adults in Korea.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Although previous studies have examined the efficacy of pitavastatin, its tolerability and effects on lipid concentrations have not been compared with those of atorvastatin in a multicenter, randomized study. OBJECTIVE: This trial compared the efficacy and tolerability of pitavastatin a...See full text at original site
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引用元：
https://doi.org/10.1016/j.clinthera.2007.11.002

データ提供：米国国立医学図書館（NLM）

Pitavastatin vs. Atorvastatin: A Comparison in Hypercholesterolemia

In the vast desert of cardiovascular health, we’re constantly searching for the most effective ways to manage cholesterol levels. This research compares the efficacy and tolerability of two statin medications – pitavastatin and atorvastatin – in patients with hypercholesterolemia. This is akin to a detailed examination of two different desert oases, carefully analyzing their resources and potential benefits. The researchers conducted a randomized, open-label, dose-titration study, comparing the effects of pitavastatin and atorvastatin on lipid levels and overall tolerability. This meticulous approach is like meticulously measuring the amount of water available in each oasis, ensuring a thorough understanding of the treatment options.

Pitavastatin and Atorvastatin: Similar Effectiveness

The study’s findings indicate that both pitavastatin and atorvastatin were equally effective in reducing LDL cholesterol levels and achieving lipid goals in patients with hypercholesterolemia. This is like finding two oases with similar water sources, offering comparable resources for sustaining life. Furthermore, both medications were well-tolerated, with no significant differences in side effect profiles. This finding is like discovering two oases that are equally hospitable and safe for travelers.

Managing Cholesterol: A Personalized Approach

This research provides valuable insights into the treatment of hypercholesterolemia, highlighting the importance of individualized care. The study’s findings suggest that both pitavastatin and atorvastatin are effective options, and the choice of medication should be based on factors such as patient preference, cost, and potential side effects. This is like choosing the best oasis for a specific journey, taking into account the needs and preferences of the traveler.

Dr.Camel’s Conclusion

This research provides a valuable comparison of two statin medications for managing hypercholesterolemia. Like a skilled desert guide offering tailored advice to travelers, the researchers have shed light on the benefits and challenges of different treatment options, helping us make informed decisions about patient care.
Date :
  1. Date Completed 2008-02-20
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

18158077

DOI: Digital Object Identifier

10.1016/j.clinthera.2007.11.002

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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