The therapy of multiple sclerosis with immune-modulating or immunosuppressive drug. A critical evaluation based upon evidence based parameters and published systematic reviews.

Author: ClericoMarinella, ContessaGiulia, DurelliLuca, RivoiroChiara, VigliettiDaniela

Paper Details 
Original Abstract of the Article :
Today many different drugs are available for treatment of multiple sclerosis (MS). Interferons, glatiramer acetate, mitoxantrone, and natalizumab have been approved by the regulatory authorities of many countries for the treatment of MS. Evidence based medicine (EBM) principles allow physicians to b...See full text at original site
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引用元:
https://doi.org/10.1016/j.clineuro.2007.10.020

データ提供:米国国立医学図書館(NLM)

Multiple Sclerosis Treatment: A Critical Evaluation of Immune-Modulating and Immunosuppressive Drugs

Multiple sclerosis (MS) is a debilitating autoimmune disease that affects the central nervous system. This study provides a comprehensive review of various drugs used to treat MS, focusing on immune-modulating and immunosuppressive therapies. The researchers critically evaluate the evidence for each drug, drawing on evidence-based medicine (EBM) principles to assess their efficacy and safety. Their findings provide a valuable guide for clinicians seeking to optimize MS treatment.

Navigating the Landscape of MS Treatment: A Guide to Evidence-Based Therapy

The researchers found that interferon beta, a widely used MS treatment, is a strong contender, particularly when administered at high doses and with frequent injections. They also highlighted the efficacy of glatiramer acetate, mitoxantrone, and natalizumab, while acknowledging the potential for toxic effects. This review emphasizes the importance of evidence-based medicine in guiding MS treatment, ensuring that patients receive the most effective and safe therapies. Remember, a wise camel always relies on reliable guides to navigate the complex terrain of MS treatment, selecting the path that leads to the best outcomes.

Managing Multiple Sclerosis: A Multifaceted Approach to Effective Treatment

This study provides a valuable overview of the various drug options available for MS treatment. It emphasizes the importance of evidence-based medicine in guiding treatment decisions, ensuring that patients receive the most effective and safe therapies. By understanding the strengths and limitations of each drug, clinicians can tailor treatment plans to individual patient needs, leading to better outcomes. Like a camel caravan traversing a challenging desert landscape, MS treatment requires a multifaceted approach, incorporating a variety of strategies to effectively manage this complex disease.

Dr.Camel's Conclusion

This comprehensive review provides valuable insights into the world of MS treatment, highlighting the importance of evidence-based medicine and individualized approaches. By understanding the efficacy and safety of different drug options, clinicians can provide the best possible care for patients with MS. Remember, a wise camel always seeks the best path through the desert, just as clinicians strive to find the optimal treatment for those navigating the challenging terrain of MS.

Date :
  1. Date Completed 2008-12-16
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

18164542

DOI: Digital Object Identifier

10.1016/j.clineuro.2007.10.020

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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