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Luteinizing hormone (LH) and estradiol suppression and growth in girls with central precocious puberty: is more suppression better? Are pre-injection LH levels useful in monitoring treatment?
Author: KleinKaren Oerter, KunzGregory J, ShermanTami Irwin
Original Abstract of the Article :
CONTEXT: Girls with central precocious puberty (CPP) are treated with gonadotropin releasing hormone (GnRH) analogues to suppress puberty. Gonadotropin levels are used to monitor treatment, since estradiol is difficult to measure at low levels. The optimal degree of hormonal suppression is still unk...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1515/jpem.2007.20.11.1189
データ提供:米国国立医学図書館(NLM)
Luteinizing Hormone (LH) and Estradiol Suppression and Growth in Girls with Central Precocious Puberty: Is More Suppression Better? Are Pre-Injection LH Levels Useful in Monitoring Treatment?
The field of [central precocious puberty (CPP)] is focused on finding the best ways to manage this condition and ensure optimal growth and development in affected children. This research explores the role of gonadotropin-releasing hormone (GnRH) analogues in suppressing puberty in girls with CPP. The researchers investigated the relationship between LH and estradiol suppression and growth outcomes in girls receiving leuprolide acetate depot treatment. They also assessed the potential of pre-injection LH levels as a useful monitoring tool.
The study's findings suggest that greater LH suppression may lead to improved height outcomes in girls with CPP. The researchers also found that pre-injection LH levels may be a valuable tool for monitoring treatment. The study highlights the importance of individualizing treatment approaches based on individual patient responses and emphasizes the need for ongoing research to optimize GnRH analogue treatment for CPP.
Navigating the Complexities of Puberty
This research is a journey through the complexities of puberty, investigating the optimal strategies for managing CPP and ensuring healthy growth and development. It's like navigating a shifting sand dune, understanding the interplay of hormones and growth is key to finding the right path.
The Importance of Individualized Care for CPP
This research underscores the importance of individualized care for children with CPP. It highlights the need to tailor treatment approaches based on individual patient responses and the value of careful monitoring to ensure optimal outcomes. It's like choosing the right camel for a long desert journey, a reliable and trustworthy companion for a smooth and successful voyage.
Dr.Camel's Conclusion
This research provides valuable insights into the management of central precocious puberty in girls. The findings highlight the importance of individualizing treatment approaches, monitoring LH suppression, and considering the potential benefits of greater suppression to optimize growth outcomes. It's a reminder that the desert of pediatric endocrinology is filled with hidden treasures, waiting to be discovered.
Date :
- Date Completed 2008-01-29
- Date Revised 2019-09-07
Further Info :
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