Predictors of response to monoamine oxidase inhibitors: do they exist?

Author: DavidsonJ R, GillerE L, HelmsM J, ZisookS

Paper Details 
Original Abstract of the Article :
Multiple regression analysis was conducted on potential response predictors in a double-blind study of monoamine oxidase inhibitors (MAOI) and placebo treatment in 130 depressed outpatients. Positive main effects were found for sex (female), lack of prior hospitalization, presence of precipitating e...See full text at original site
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引用元:
https://doi.org/10.1007/BF02219719

データ提供:米国国立医学図書館(NLM)

Unraveling the Mysteries of Monoamine Oxidase Inhibitors (MAOIs)

The vast and complex desert of mental health research is constantly evolving, with new discoveries and approaches emerging like oases in a parched landscape. This study, like a seasoned traveler navigating this terrain, seeks to identify predictors of response to monoamine oxidase inhibitors (MAOIs), a class of drugs used to treat depression. The authors, like explorers seeking a hidden treasure, investigate potential factors that might predict a successful response to MAOI treatment.

Predicting Success in Depression Treatment

This study, like a camel carefully selecting its route through the desert, examined a range of potential predictors of response to MAOIs. The findings suggest that certain factors, such as being female, lack of prior hospitalization, and the presence of precipitating events, may be associated with a more positive response to treatment. This is like a camel finding a water source that's particularly well-suited for its needs, leading to a more successful journey. However, the authors acknowledge that the relationship between these factors and treatment response is complex and requires further investigation.

The Journey of Depression Treatment

The study highlights the importance of personalized approaches to depression treatment. It suggests that a one-size-fits-all approach may not be the most effective. Understanding individual characteristics and tailoring treatment plans accordingly can improve the likelihood of a successful outcome. This is like a camel adapting its strategy to navigate different types of terrain, ensuring a smoother and more successful journey.

Dr. Camel's Conclusion

This study is a reminder that the journey of depression treatment is complex and often unpredictable. The authors' findings, like a beacon guiding travelers through a vast and desolate landscape, offer valuable insights into the potential predictors of response to MAOIs. However, the research also underscores the importance of ongoing research to further refine our understanding of this class of drugs and how to optimize their use in clinical practice.

Date :
  1. Date Completed 1992-03-27
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

1824048

DOI: Digital Object Identifier

10.1007/BF02219719

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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