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Transdermal and dermal delivery of adefovir: effects of pH and permeation enhancers.
Author: HolýAntoni N, HrabálekAlexandr, KlimentováJana, LorencováKaterina, NovotnýJakub, VávrováKaterina
Original Abstract of the Article :
The objective of this work was to investigate feasibility of transdermal and dermal delivery of adefovir (9-(2-phosphonomethoxyethyl)adenine), a broad-spectrum antiviral from the class of acyclic nucleoside phosphonates. Transport of 2% adefovir through and into porcine skin and effects of various s...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.ejpb.2007.12.005
データ提供:米国国立医学図書館(NLM)
Delivering Adefovir: A New Path in Antiviral Therapy
The desert of viral infections is vast and complex, requiring innovative solutions. This research explores the potential of transdermal and dermal delivery of adefovir, an antiviral medication. The study investigates the factors influencing the delivery of adefovir through the skin, including pH, solvents, and permeation enhancers. These factors are like the different paths and obstacles one might encounter while navigating a desert.
A New Route Through the Desert of Viral Infections
The study found that adefovir could be successfully delivered through the skin, suggesting a potential alternative route of administration for this antiviral medication. The researchers identified key factors that influence adefovir delivery, such as pH and the use of permeation enhancers. This discovery could lead to new and potentially more effective ways to deliver antiviral medications, opening up new avenues for treatment.
Exploring New Pathways in Antiviral Therapy
This research highlights the potential of transdermal and dermal delivery of adefovir as a novel approach to antiviral therapy. The study suggests that by optimizing delivery methods and understanding the factors influencing skin penetration, we can potentially improve the effectiveness of antiviral treatments. It's like finding a new path through a desert landscape, offering a more efficient and effective route for reaching our destination.
Dr. Camel's Conclusion
This study points to the potential of transdermal and dermal delivery of adefovir as a promising approach to antiviral therapy. It's like discovering a hidden path through the desert, leading to a more efficient and effective way to combat viral infections. This research offers valuable insights into the possibilities of alternative delivery methods for antiviral medications, potentially leading to new treatment strategies and improved outcomes for patients.
Date :
- Date Completed 2008-08-29
- Date Revised 2014-11-20
Further Info :
Related Literature
English
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