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Chronology of panic and avoidance, age of onset in panic disorder, and prediction of treatment response. A report from the Cross-National Collaborative Panic Study.

Author: BenkertO, BullerR, GoldenbergI M, LavoriP W, MaierW

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study explored the relationship between the timing of panic disorder and avoidance behavior, and their impact on treatment outcomes. Patients who developed avoidance behavior before experiencing full-blown panic disorder had less severe agoraphobia but showed no difference in treatment response. Early onset of panic disorder was associated with a higher prevalence of agoraphobia. However, the timing of panic disorder or avoidance behavior did not predict treatment outcomes with alprazolam or imipramine.
Paper Details　
Original Abstract of the Article :
The relevance of the chronology between panic disorder and avoidance behavior and of an early, medium or late onset of panic disorder was tested. Groups from the sample of the cross-national collaborative panic study (CNCPS) were compared for differences in basic characteristics and for the ability ...See full text at original site
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引用元：
https://doi.org/10.1007/BF02190758

データ提供：米国国立医学図書館（NLM）

Chronology of Panic and Avoidance: Predicting Treatment Response

The study of panic disorder, a debilitating condition characterized by anxiety attacks and avoidance behaviors, is a challenging journey through a vast and often unpredictable desert. This research investigates the relationship between the chronology of panic disorder and avoidance behavior and the age of onset of panic disorder. The researchers analyzed data from the Cross-National Collaborative Panic Study (CNCPS), a large international study of panic disorder. They found that patients who developed avoidance behavior before the full syndrome of panic disorder were less likely to develop agoraphobia but did not differ in their response to treatment. The study also found that patients with an early onset of panic disorder were more likely to develop agoraphobia. However, the age of onset of panic disorder did not predict treatment response.

Chronology and Age of Onset: Limited Predictive Value for Treatment Response

The study's findings suggest that the chronology of panic disorder and avoidance behavior and the age of onset of panic disorder are not strong predictors of treatment response. While these factors may influence the development of agoraphobia, they do not necessarily determine how well patients will respond to treatment.

Panic Disorder: A Complex and Multifaceted Condition

Panic disorder is a complex and multifaceted condition. The best treatment approach will vary depending on the individual patient's characteristics, including the chronology of their symptoms, the age of onset, and the severity of their condition.

Dr.Camel's Conclusion

The desert of panic disorder research is vast and complex. This study provides valuable insights into the relationship between the chronology of panic disorder and avoidance behavior, and the age of onset, and their potential impact on treatment response. While these factors may influence the development of agoraphobia, they do not necessarily predict treatment outcomes.

Date :
  1. Date Completed 1991-06-18
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

1827602

DOI: Digital Object Identifier

10.1007/BF02190758

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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