Botulinum toxin type-B improves sialorrhea and quality of life in bulbaronset amyotrophic lateral sclerosis.

Author: CoelhoMiguel, CostaJoão, EvangelistaTeresinha, FerreiraJoaquim, RochaMaria Luz, de CarvalhoMamede

Paper Details 
Original Abstract of the Article :
BACKGROUND: Sialorrhea is a disabling problem in bulbaronset amyotrophic lateral sclerosis (ALS). Botulinum toxin (BTX) type A and B have been proposed as alternatives to traditional treatments. OBJECTIVES: To evaluate the efficacy and safety of BTX type B in the treatment of sialorrhea in patients...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/s00415-008-0738-5

データ提供:米国国立医学図書館(NLM)

Botulinum Toxin Type-B: A New Oasis for Sialorrhea in Amyotrophic Lateral Sclerosis

I'm Dr. Camel, and I'm always on the lookout for new treatments that can provide relief for debilitating conditions. Amyotrophic lateral sclerosis (ALS), a neurodegenerative disease, can cause sialorrhea, excessive drooling, which can significantly impact quality of life. It's like navigating a desert where the body's systems are slowly breaking down. This study examines the efficacy and safety of botulinum toxin type-B (BTX-B) for treating sialorrhea in patients with bulbar-onset ALS, a form of ALS that affects the muscles involved in speech and swallowing. It's like searching for a new source of water in a parched desert, seeking to alleviate a distressing symptom.

BTX-B: A Potential Oasis for Relief

The study found that BTX-B injections were effective in reducing sialorrhea and improving quality of life for patients with bulbar-onset ALS. It's like finding a well that provides a steady supply of water, offering relief and sustenance in the desert of ALS. The researchers reported a significant reduction in drooling and an improvement in patients' ability to manage their condition. It's like creating a more stable and navigable environment in the desert, allowing patients to live with more comfort and dignity.

Hope in the Desert of ALS

This study offers hope for patients with ALS who experience sialorrhea. It's like finding a new oasis in a vast and unforgiving desert, offering relief from a challenging symptom. The research highlights the potential of BTX-B as a safe and effective treatment option, improving quality of life and providing a better experience for those living with ALS.

Dr.Camel's Conclusion

This study provides compelling evidence for the efficacy and safety of botulinum toxin type-B injections in treating sialorrhea in patients with bulbar-onset ALS. It's like discovering a new spring in the desert of ALS, offering a source of relief and hope. This research underscores the importance of ongoing research and development of innovative treatments for this challenging disease.
Date :
  1. Date Completed 2008-07-01
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18283399

DOI: Digital Object Identifier

10.1007/s00415-008-0738-5

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.