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[Antihypertensive efficacy of the combination of captopril 50mg and hydrochlorothiazide 25mg evaluated by ambulatory blood pressure measurement].

Author: AsmarR, BenetosA, BoulangerP, DarneB, LaurentS, SafarM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

The captopril-hydrochlorothiazide combination administered once daily was effective in reducing blood pressure in 51 patients with moderate essential hypertension. Mean systolic and diastolic blood pressure were significantly reduced over 24 hours, with no change in heart rate.
Paper Details　
Original Abstract of the Article :
The anti-hypertensive effects of the captopril-hydrochlorothiazide combination administered during three months as one single morning dose were evaluated in 51 patients with moderate essential hypertension by means of ambulatory blood pressure recording. At the end of the study, the mean values of a...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1831894

データ提供：米国国立医学図書館（NLM）

A Winning Combination for High Blood Pressure

High blood pressure, or hypertension, is a silent but dangerous desert storm that can wreak havoc on the body.

Our research investigated the effectiveness of combining captopril, an ACE inhibitor, with hydrochlorothiazide, a diuretic, in managing moderate essential hypertension. This is like combining the best of both worlds in a desert expedition – using a sturdy camel for strength and a resourceful guide for navigation.

A Powerful Duo

We found that this drug combination significantly lowered blood pressure in patients with moderate hypertension, both during the day and night. This is like a camel caravan carefully navigating a diverse desert landscape, adapting its strategy to different terrains and weather conditions.

Managing High Blood Pressure

Our research provides evidence for the efficacy of this drug combination in managing high blood pressure. This finding can guide clinicians in developing personalized treatment plans for patients with hypertension.

Dr. Camel's Conclusion

This research suggests that combining captopril and hydrochlorothiazide can be a powerful tool in managing high blood pressure, offering a safe and effective way to navigate the challenging landscape of this common condition.

Date :
  1. Date Completed 1991-10-01
  2. Date Revised 2016-12-09
Further Info :

Pubmed ID

1831894

DOI: Digital Object Identifier

1831894

Related Literature

Article Analysis
・Effects of captopril and hydrochlorothiazide
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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