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An open study of Triphasil and Diane 50 in the treatment of acne.

Author: WishartJ M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Both Triphasil, containing levonorgestrel, and Diane, containing cyproterone acetate, effectively reduced acne counts in 20 patients with similar acne severity. Diane produced more marked hormonal changes.
Paper Details　
Original Abstract of the Article :
Levonorgestrel, as used in oral contraceptives, has antiovulatory activity at doses far lower than those producing androgenic effects. Triphasil, containing levonorgestrel was compared with Diane, containing cyproterone acetate in a trial of acne treatment. Twenty closely matched patients were alter...See full text at original site
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引用元：
https://doi.org/10.1111/j.1440-0960.1991.tb00683.x

データ提供：米国国立医学図書館（NLM）

Acne Treatment: A Hormonal Approach

This research compares the efficacy of two oral contraceptives, Triphasil and Diane 50, in treating acne. The study involved 20 patients who were randomly assigned to receive either Triphasil or Diane for 6 months. Both groups showed significant improvement in acne counts, with Diane demonstrating a slightly greater reduction in acne severity. The study suggests that both oral contraceptives can be effective in treating acne, likely by modulating hormonal activity.

Hormonal Harmony: Balancing Beauty and Well-being

This study demonstrates the potential of hormonal therapy for treating acne. It's like finding a harmonious balance in a desert ecosystem – regulating hormonal activity can restore the natural balance of the body. The study's findings offer hope for individuals struggling with acne, suggesting that hormonal therapy could be a valuable treatment option for managing this common skin condition. It also highlights the importance of considering the broader impact of hormonal changes on overall health and well-being.

The Desert of Acne: Seeking Clarity

Acne is a common skin condition that can cause significant distress and impact self-esteem. This research underscores the importance of exploring different treatment options, including hormonal therapy. It's like searching for a hidden oasis in the desert of acne – finding the right solution can make a world of difference. The study's findings encourage us to consider a holistic approach to acne treatment, taking into account individual needs and potential side effects.

Dr.Camel's Conclusion

This research offers valuable insights into the potential of oral contraceptives for treating acne. It's a reminder that finding the right treatment for a skin condition can involve exploring different approaches and understanding the complex interplay of hormones and skin health. Just as the desert offers a diverse landscape, our bodies are intricate ecosystems that require a personalized approach to care.

Date :
  1. Date Completed 1991-10-29
  2. Date Revised 2019-09-18
Further Info :

Pubmed ID

1834045

DOI: Digital Object Identifier

10.1111/j.1440-0960.1991.tb00683.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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