Meta-analysis: remission and response from control arms of randomized trials of biological therapies for active luminal Crohn's disease.

Author: CottoneM, MocciaroF, OlivoM, OrlandoA, RossiF, ScimecaD, SferrazzaA, TinèF

Paper Details 
Original Abstract of the Article :
BACKGROUND: Remission and response are the main outcomes to evaluate the efficacy of new treatments for Crohn's disease (CD). AIM: To explain variation of remission and response rates in active luminal CD. METHODS: We studied control patients from trials of biological therapies through articles re...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2036.2008.03681.x

データ提供:米国国立医学図書館(NLM)

Luminal Crohn's Disease: A Desert of Uncertainty

Crohn's disease, a chronic inflammatory bowel disease, is a complex condition with variable treatment responses. This meta-analysis explores remission and response rates in control arms of randomized trials of biological therapies for active luminal Crohn's disease. Imagine a desert landscape, where the path to recovery is often unclear and unpredictable. Researchers sought to understand the variability in treatment outcomes, hoping to shed light on the best strategies for managing this disease.

Remission and Response: Navigating the Desert's Variability

The meta-analysis revealed significant heterogeneity in remission and response rates across different studies, highlighting the need for a more nuanced understanding of treatment responses in luminal Crohn's disease. The findings suggest that factors like the time of outcome evaluation and the specific criteria used to define remission and response can influence results. This insight, like a compass guiding a traveler through a desert, can help researchers better understand the factors contributing to variability in treatment outcomes.

Health Guidance: Individualized Treatment Approaches

Living with Crohn's disease requires a collaborative approach between patients and healthcare professionals. Understanding the factors that influence treatment responses is crucial for developing personalized treatment plans. Remember, the journey through Crohn's disease is often a personal one, requiring individualization of treatment strategies to find the most effective path to recovery.

Dr.Camel's Conclusion

This meta-analysis underscores the need for a deeper understanding of treatment responses in luminal Crohn's disease, emphasizing the importance of individualized approaches to care. The findings are like a desert map, revealing the complexities of this disease and the need for ongoing research to identify the best strategies for achieving remission and improving quality of life for patients.

Date :
  1. Date Completed 2008-08-01
  2. Date Revised 2008-05-20
Further Info :

Pubmed ID

18346185

DOI: Digital Object Identifier

10.1111/j.1365-2036.2008.03681.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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