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Safety of multiple doses of ofloxacin in healthy volunteers.

Author: BealsB S, FlorS C, SteinG E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Ofloxacin, a new fluoroquinolone antibiotic, was found to be safe and have a low potential for toxicity in a study of 12 healthy male volunteers. The most frequent side effects were gastrointestinal complaints, such as nausea, diarrhea, and upset.
Paper Details　
Original Abstract of the Article :
A safety profile of ofloxacin, a new fluoroquinolone antibiotic, was assessed in twelve healthy male volunteers. Ofloxacin was dosed at 400 mg twice daily over a 10-day course of treatment. This evaluation included chemistry and haematologic profiles, neurologic evaluations, ophthalmologic examinati...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1841044

データ提供：米国国立医学図書館（NLM）

Ofloxacin: A New Fluoroquinolone with a Favorable Safety Profile

Ofloxacin, a new fluoroquinolone antibiotic, is a promising treatment option for various bacterial infections. This study assessed the safety of ofloxacin in healthy volunteers, examining its impact on various physiological parameters.

Think of this research as a careful exploration of a new desert path, where the researchers are testing the safety and effectiveness of a new drug. They are carefully monitoring the volunteers' health to determine if ofloxacin is safe and well-tolerated.

Ofloxacin: A Safe and Well-Tolerated Antibiotic

The study found that ofloxacin was safe and well-tolerated in healthy volunteers. The most common side effects were gastrointestinal, and no serious adverse events were reported.

A Promising New Antibiotic

This research provides reassurance about the safety of ofloxacin, suggesting that it may be a valuable addition to the antibiotic arsenal for treating various bacterial infections.

Dr.Camel's Conclusion

This study offers valuable insights into the safety profile of ofloxacin. It suggests that this new fluoroquinolone antibiotic has a favorable safety profile and may be a promising option for treating bacterial infections.

Date :
  1. Date Completed 1992-11-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1841044

DOI: Digital Object Identifier

1841044

Related Literature

Article Analysis
・Side Effects of ofloxacin・Effects of ofloxacin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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