Pancreaticoduodenectomy (classic Whipple) versus pylorus-preserving pancreaticoduodenectomy (pp Whipple) for surgical treatment of periampullary and pancreatic carcinoma.

Author: AntesG, BuchlerM W, DienerM K, HeukauferC, KnaebelH P, SchwarzerG, SeilerC M

Paper Details 
Original Abstract of the Article :
Pancreatic cancer is the fourth leading cause of cancer death for men and the fifth for women. The standard treatment for resectable tumours is either a classic Whipple operation or a pylorus-preserving pancreaticoduodenectomy but it is still unclear which of the two procedures is more favourable in...See full text at original site
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引用元:
https://doi.org/10.1002/14651858.CD006053.pub2

データ提供:米国国立医学図書館(NLM)

Whipple vs. pp Whipple: Choosing the Right Surgery for Pancreatic Cancer

Pancreatic cancer, like a relentless desert wind, poses a formidable challenge to medical professionals. This study compares two surgical procedures for treating pancreatic cancer, the classic Whipple operation and the pylorus-preserving pancreaticoduodenectomy (pp Whipple). The researchers investigated the impact of these procedures on survival, mortality, complications, and overall quality of life in patients with pancreatic cancer.

Comparing the Outcomes of Two Surgical Procedures

The study found that both the classic Whipple operation and the pp Whipple procedure were effective in treating pancreatic cancer. However, there were some differences in outcomes. The pp Whipple procedure was associated with a higher risk of complications, but it also offered potential benefits in terms of quality of life, as it preserved the pylorus, a part of the stomach that helps regulate food passage. The study highlights the need for a careful evaluation of individual patients to determine the most appropriate surgical approach.

Implications for Pancreatic Cancer Treatment

This research underscores the complexities of treating pancreatic cancer and the importance of considering individual patient factors when choosing a surgical procedure. The study provides valuable information about the potential benefits and risks of both the classic Whipple operation and the pp Whipple procedure. Further research is needed to determine the optimal approach for different patients and to explore ways to minimize the risk of complications.

Dr. Camel's Conclusion

This research highlights the ongoing efforts to improve the treatment of pancreatic cancer. By comparing two surgical procedures, researchers have provided valuable insights that can guide clinical decision-making. As we continue to delve deeper into the complexities of this disease, we may discover even more effective and personalized treatments for pancreatic cancer patients.

Date :
  1. Date Completed 2008-06-13
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

18425935

DOI: Digital Object Identifier

10.1002/14651858.CD006053.pub2

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SNS
PICO Info
in preparation
Languages

English

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