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Acute toxic effects of sustained-release verapamil in chronic renal failure.

Author: BiermanM H, HammekeM D, PritzaD R

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Sustained-release verapamil, a calcium channel blocker, can lead to acute toxic effects in hypertensive patients with chronic renal insufficiency or end-stage renal disease. Patients should be monitored closely for adverse cardiovascular, metabolic, and hepatic side effects.
Paper Details　
Original Abstract of the Article :
Four hypertensive patients with chronic renal insufficiency or end-stage renal disease who were treated with sustained-release verapamil hydrochloride subsequently developed acute toxic effects. All four patients developed varying degrees of atrioventricular heart block, hypotension, hyperkalemia, m...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1843183

データ提供：米国国立医学図書館（NLM）

Verapamil: A Cautionary Tale in the Desert of Renal Impairment

Verapamil, a medication used to treat hypertension, can present unique challenges in patients with renal impairment. This study examines the potential toxic effects of sustained-release verapamil in individuals with chronic renal insufficiency or end-stage renal disease. The research highlights the importance of careful monitoring and individualized treatment approaches in this patient population.

Verapamil: A Potentially Toxic Journey for Patients with Renal Impairment

The study reveals that sustained-release verapamil can accumulate in patients with renal impairment, leading to potentially serious adverse effects, such as heart block, hypotension, hyperkalemia, and hepatic dysfunction. It's like navigating a desert with a dwindling water supply—careful management and monitoring are crucial.

Navigating the Desert of Renal Impairment

This research emphasizes the importance of individualized treatment approaches for patients with renal impairment. Careful monitoring and close communication with healthcare providers are vital for ensuring safety and optimal outcomes.

Dr.Camel's Conclusion

This study underscores the potential risks associated with verapamil in patients with renal impairment. It's a reminder that navigating the desert of chronic illness requires careful consideration of medication choices and vigilant monitoring.

Date :
  1. Date Completed 1991-11-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1843183

DOI: Digital Object Identifier

1843183

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