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Biphosphonates for the therapy of complex regional pain syndrome I--systematic review.

Author: BachmannLucas M, BrunnerFlorian, HeldUlrike, KisslingRudolf, SchmidAnnina

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

A systematic review was conducted to assess the benefit of bisphosphonates in the treatment of CRPS I patients with bone loss.
Paper Details　
Original Abstract of the Article :
Several studies found that biphosphonates counteract locally increased bone resorption and associated pain in patients with complex regional pain syndrome I (CRPS I). We performed a systematic review of all randomised controlled trials to assess the benefit of biphosphonates in the treatment of CRPS...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejpain.2008.03.005

データ提供：米国国立医学図書館（NLM）

Biphosphonates: A Potential Treatment for Complex Regional Pain Syndrome I

Complex Regional Pain Syndrome I (CRPS I) is a debilitating condition characterized by chronic pain and other symptoms. This study explores the potential of biphosphonates, a class of drugs typically used to treat osteoporosis, as a treatment for CRPS I patients with bone loss. The researchers conducted a systematic review of all randomized controlled trials to assess the effectiveness of biphosphonates in treating CRPS I.

A New Approach to Treating Chronic Pain

The study's findings suggest that biphosphonates may be beneficial for reducing pain in CRPS I patients with bone loss. The researchers observed a positive effect of biphosphonates on pain relief in several studies. This suggests that biphosphonates' ability to counteract bone resorption may play a role in pain reduction, particularly in CRPS I patients with bone loss.

Navigating the Desert of Chronic Pain

This research offers a potential new avenue for treating CRPS I, a condition that often leaves patients struggling for relief. While further research is needed to confirm the efficacy of biphosphonates for this indication, this study provides a promising avenue for exploration. The study serves as a reminder that the desert of chronic pain is complex and multifaceted, requiring continuous exploration and innovation to develop effective treatment strategies.

Dr.Camel's Conclusion

This study is a beacon of hope in the desert of chronic pain. The potential of biphosphonates to provide relief for CRPS I patients is a significant finding. This research underscores the importance of seeking innovative solutions for conditions that often defy conventional treatment approaches.

Date :
  1. Date Completed 2009-04-10
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

18440845

DOI: Digital Object Identifier

10.1016/j.ejpain.2008.03.005

SNS
PICO Info
in preparation
Languages

English

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