[Efficacy of levofloxacin-based triple therapy as second-line Helicobacter pylori eradication].

Author: BaikSu Jung, HaChang Yoon, JungHae Sun, JungJi Min, JungSung-Ae, KangMin-Jung, NaYoun Ju, ShimKi-Nam, YooKwon

Paper Details 
Original Abstract of the Article :
Bismuth-based quadruple therapy for second-line eradication treatment achieves the eradication rate ranging from 70% to 81% due to antimicrobial resistance and poor compliance. The aim of this study was to compare the eradication rate of levofloxacin-based triple therapy with that of bismuth-based q...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/18516012

データ提供:米国国立医学図書館(NLM)

Levofloxacin-Based Triple Therapy: A Second-Line Defense Against H. pylori

The battle against [Helicobacter pylori (H. pylori)] infection requires effective treatment strategies. This research examines the efficacy of [levofloxacin-based triple therapy] as a second-line treatment option for H. pylori eradication. The authors conducted a comparative study, comparing the eradication rates of levofloxacin-based triple therapy with [bismuth-based quadruple therapy]. Their findings suggest that levofloxacin-based triple therapy may be a viable alternative to bismuth-based quadruple therapy in cases of H. pylori resistance.

Navigating the Shifting Sands of H. pylori Resistance

The study found that levofloxacin-based triple therapy achieved comparable eradication rates to bismuth-based quadruple therapy, suggesting its potential as a second-line treatment option. This is particularly important in light of the increasing prevalence of H. pylori resistance to conventional therapies.

The Importance of Adaptability

As Dr. Camel, I believe that this research highlights the importance of adapting treatment strategies to address evolving challenges like antimicrobial resistance. The development of new and effective therapies, like levofloxacin-based triple therapy, is crucial for maintaining the effectiveness of H. pylori eradication efforts.

Dr.Camel's Conclusion

This research compares the eradication rates of levofloxacin-based triple therapy with bismuth-based quadruple therapy in patients with Helicobacter pylori resistance. The study suggests that levofloxacin-based triple therapy may be a viable alternative to bismuth-based quadruple therapy, offering a promising second-line treatment option. As Dr. Camel, I believe that this research underscores the need for adaptability and innovation in the face of evolving challenges in infectious disease management.

Date :
  1. Date Completed 2008-12-31
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

18516012

DOI: Digital Object Identifier

200805254

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PICO Info
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Languages

Korean

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